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Kyro

French Bulldog

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“Our super sweet chocolate powerhouse.”

This dog has been viewed 356 times and been given 0 wags

Genetic Breed Result

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French Bulldog

French Bulldog French Bulldog
French Bulldogs, affectionately known by their many fans as Frenchies, are an immensely popular and well-known breed of dog. As their name implies, they are native to France and are the result of a mix between English Bulldogs and local dogs in Paris. They are very popular around the world, earning their place as the 4th most popular dog in the United Kingdom and the 9th most popular dog in the United States.
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Genetic Stats


Predicted Adult Weight
Genetic Age
36 human years Learn More
Based on the date of birth provided

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Health Summary

Kyro is at increased risk for one genetic health condition.

Intervertebral Disc Disease (Type I)

Kyro inherited both copies of the variant we tested

How to interpret this result

Kyro has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Breed-Relevant Genetic Conditions

Progressive Retinal Atrophy - crd4/cord1 (RPGRIP1)

Identified in French Bulldogs

Canine Multifocal Retinopathy (BEST1 Exon 2)

Identified in French Bulldogs

Hereditary Cataracts (HSF4 Exon 9 Boston Terrier Variant)

Identified in French Bulldogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in French Bulldogs

Additional Genetic Conditions


Clinical Tools

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
Can have a melanistic mask (EmEm)
K Locus (CBD103)
More likely to have a mostly solid black or brown coat (KBky)
Intensity Loci LINKAGE
No impact on coat pattern (Dilute Red Pigmentation)
A Locus (ASIP)
Not expressed (ayat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (Dd)
B Locus (TYRP1)
Black or gray hair and skin (BB)
S Locus (MITF)
Likely solid colored, but may have small amounts of white (Ssp)
H Locus (Harlequin)
hh
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely short muzzle (AA)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Smaller (II)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Intermediate (TA)
Body Size (GHR - E191K)
Intermediate (GA)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Kyro’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A234

Map

A1e

Kyro’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A234

Kyro’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs in village dogs in South America, South Asia, and into the South Pacific. Among breeds, we see it in highest frequency among Vizslas, Boxers, and Yorkshire Terriers.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

Through Kyro’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7

Map

D

Kyro’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7

Kyro’s Haplotype

Part of the D haplogroup, this common haplotype has been found in French Bulldogs, Afghan Hounds, Bull Terriers, and village dogs spanning from South America to Africa and into the South Pacific.

Some other Embark dogs with this haplotype:

The D paternal lineage is common in Boxers.