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Kyoto

Mixed Ancestry

“Adopted in July 2012, estimated to be 3-5 years old at the time. The shelter told us he was rescued from the streets of Georgia, USA. What a weirdo. He's an incredibly picky eater, always playing with his food before deciding if it is worthy of consuming. He holds treats and toys in his paws like a cat. Does not lick anyone or anything ever. Has a vague understanding of common dog commands but doesn't fully grasp them, such as saying "sit" will result in him lying down. A loveable quirky boy.”

Current Location

Randolph, New Jersey, USA

From

Mt Pleasant Animal Shelter, New Jersey 10, East Hanover, NJ, USA

This dog has been viewed and been given 3 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Dogs Like Kyoto

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Discover dogs who share a similar breed mix to Kyoto. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
German Shepherd Dog
Siberian Husky
American Pit Bull Terrier
Chow Chow
Rottweiler
Golden Retriever
Boxer
Supermutt

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Here’s what Kyoto’s family tree may have looked like.
Kyoto
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed German Shepherd Dog mix American Pit Bull Terrier / Golden Retriever mix Chow Chow / Rottweiler mix German Shepherd Dog Siberian Husky mix American Pit Bull Terrier Golden Retriever mix Chow Chow mix Rottweiler mix German Shepherd Dog German Shepherd Dog Siberian Husky Siberian Husky mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Kyoto’s breed mix.
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Health Summary

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Kyoto inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Kyoto inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Kyoto’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Kyoto is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Exercise-Induced Collapse, EIC

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Kyoto inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Kyoto’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Kyoto is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Exercise-Induced Collapse, EIC?

EIC has been linked to a mutation in the DNM1 gene, which codes for the protein dynamin. In the neuron, dynamin trucks neurotransmitter-filled vesicles from the cell body, where they are generated, to the dendrites. It is hypothesized in dogs affected with EIC, the mutation in DNM1 disrupts efficient neurotransmitter release, leading to a cessation in signalling and EIC.

ALT Activity

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Kyoto inherited both copies of the variant we tested

Why is this important to your vet?

Kyoto has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Kyoto's ALT activity above their current, healthy, ALT activity. As an increase above Kyoto’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Hemophilia A

Identified in Boxers

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Progressive Retinal Atrophy, prcd

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd2

Identified in American Pit Bull Terriers

X-Linked Progressive Retinal Atrophy 1, XL-PRA1

Identified in Siberian Huskies

Day Blindness

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers and German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

GM1 Gangliosidosis

Identified in Siberian Huskies

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Muscular Dystrophy

Identified in Golden Retrievers

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Osteogenesis Imperfecta

Identified in Golden Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Kyoto’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A211

Map

A2

Kyoto’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A211

Kyoto’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in German Shepherd Dogs, Siberian Huskies, and Alaskan Malamutes.

Dingos commonly possess this haplogroup.

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Through Kyoto’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.10

Map

A2b

Kyoto’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.10

Kyoto’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most commonly in Labrador Retrievers, Rottweilers, Curly-Coated Retrievers, Dandie Dinmont Terriers, and village dogs throughout the world.

A2b is found in the Daschund breed.

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