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Kleo

Mixed Breed

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“Adopted 9/23/18”

This dog has been viewed and been given 8 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Dogs Like Kleo

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Discover dogs who share a similar breed mix to Kleo. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Siberian Husky
German Shepherd Dog
Supermutt

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Kleo
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Siberian Husky mix Siberian Husky mix Siberian Husky Siberian Husky / German Shepherd Dog mix Siberian Husky German Shepherd Dog mix Siberian Husky Siberian Husky Siberian Husky German Shepherd Dog Siberian Husky Siberian Husky German Shepherd Dog Mixed

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Kleo’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Kleo inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Collie Eye Anomaly

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Kleo inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Kleo is unlikely to develop this condition due to the variant.

What is Collie Eye Anomaly?

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia. The choroid anchors the retina to the underlying structures and supplies it with oxygen and nourishment. CEA is a developmental disease of the choroid.

ALT Activity

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Kleo inherited one copy of the variant we tested

Why is this important to your vet?

Kleo has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kleo has this genotype, as ALT is often used as an indicator of liver health and Kleo is likely to have a lower than average resting ALT activity. As such, an increase in Kleo’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Platelet Factor X Receptor Deficiency, Scott Syndrome

Identified in German Shepherd Dogs

X-Linked Progressive Retinal Atrophy 1, XL-PRA1

Identified in Siberian Huskies

Day Blindness

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Kleo’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A465

Map

A1e

Kleo’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A465

Kleo’s Haplotype

Part of the A1e haplogroup, the A465 haplotype occurs most commonly in Siberian Huskies. It's a rare find!

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Kleo inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Kleo is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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