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“Kismik”
T'Aguhu Uzh Kismic of Zorik's Martakert

Armenian Gampr

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Armenian Gampr Club of America (AGCA):

Genetic Breed Result

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Armenian Gampr

The Armenian Gampr is an ancient, working livestock guardian dog originally bred in the southern Caucasus Mountains. The Gampr is considered a landrace rather than a breed with a closed population; they are genetically diverse with an emphasis on function rather than form. There are several regional variants of the Gampr.

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Changes to this dog’s profile
  • On 5/4/2022 changed name from "Kismik" to "T'Aguhu Uzh Kismic of Zorik's Martakert"

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Health Summary

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Kismik has one variant that you should let your vet know about.

ALT Activity

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Kismik inherited one copy of the variant we tested

Why is this important to your vet?

Kismik has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kismik has this genotype, as ALT is often used as an indicator of liver health and Kismik is likely to have a lower than average resting ALT activity. As such, an increase in Kismik’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Through Kismik’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A382

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A1a

T'Aguhu Uzh Kismic of Zorik's Martakert’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A382

T'Aguhu Uzh Kismic of Zorik's Martakert’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Labrador Retrievers, Golden Retrievers, and Chesapeake Bay Retrievers.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through Kismik’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H10.1/Hd.4

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D

T'Aguhu Uzh Kismic of Zorik's Martakert’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H10.1/Hd.4

T'Aguhu Uzh Kismic of Zorik's Martakert’s Haplotype

Part of the D haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

The D paternal lineage is common in Boxers.

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