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King

“King is a very intelligent wolfdog has a large vocabulary and very gentle with his toys. Treats a few like his babies”

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Genetic Breed Result

Learn how it’s done
45.6% German Shepherd Dog
21.2% Alaskan Malamute
19.9% Gray Wolf
13.3% Siberian Husky
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Genetic Stats


Wolfiness

35.6 % HIGH Learn More

Predicted Adult Weight
Genetic Age
39 human years Learn More
Based on the date of birth provided

DNA Breed Origins

What’s this?
Breed colors:
German Shepherd Dog
Alaskan Malamute
Gray Wolf
Siberian Husky

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Health Summary

King is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Multiple Drug Sensitivity

King inherited one copy of the variant we tested

How to interpret this result

King has one copy of a variant at the ABCB1 gene and is at risk for displaying adverse drug reactions. While he may not be as severely affected as a dog with two copies of the ABCB1 drug sensitivity allele, normal dosages of drugs could still have potentially severe effects on King. Please inform your veterinarian that King carries this variant; it is essential that they know this information before prescribing drugs.

What is Multiple Drug Sensitivity?

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with a mutation in the ABCB1 gene.

ALT Activity

King inherited one copy of the variant we tested

Why is this important to your vet?

King has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that King has this genotype, as ALT is often used as an indicator of liver health and King is likely to have a lower than average resting ALT activity. As such, an increase in King’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Factor VII Deficiency

Identified in Alaskan Malamutes

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLADIII

Identified in German Shepherd Dogs

Day Blindness

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs

Polyneuropathy, NDRG1 Malamute Variant

Identified in Alaskan Malamutes

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Agouti (Wolf Sable) coat color pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation

Through King’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A41

Map

A1d

King’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A41

King’s Haplotype

Part of the large A1d haplogroup, we have not spotted this haplotype in village dogs yet. We do see it in 3 breeds: Alaskan Malamutes, Bichon Frises, and Posavac Hounds.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

Through King’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

Achille's Haplogroup

Haplotype

Achilles

Map

Achille's Haplogroup

King’s Haplogroup

This is a lineage that is unknown in dogs and may only be found in wolves. It is very different from all known dog lineages indicating a long time between the most recent common ancestor of canids in this lineage and domestic dogs.

Achilles

King’s Haplotype

This haplotype has been spotted in wolves and dogs with wolf ancestry. Not only is that pretty neat, but it also helps move science forward.

Some other Embark dogs with this haplotype:

The mysterious wolf hides many genetic mysteries unknown to science - like where this male lineage came from.