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Kiera

Mixed Ancestry

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“Kiera is a Tamaskan dog - a new breed in development. She is a very sweet girl - high prey drive, excellent hiking companion, and we bikejor and mush (when there is enough snow)!”

Current Location

Arizona, USA

From

Pennsylvania, USA

This dog has been viewed and been given 26 wags

Registration

Tamaskan Dog Register (TDR): TDR 00721G1/2016

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Alaskan-type Husky

The Alaskan Husky is all athlete. These dogs have a wide variety of appearances because they are bred for performance and behavior rather than looks. In fact, they've been specifically bred to pull sleds for hundreds of years. In temperament, they tend to be similar to the Siberian Husky.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Alaskan Malamute

The Alaskan Malamute is a large, fluffy spitz breed recognized as being one of the most ancient breeds of dogs. The forebears to the modern Malamute crossed the Bering Strait with their owners over 4,000 years ago. Their size, thick coat, and work drive make them ideal dogs for pulling sleds, but they also make amicable companions.

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Genetic Stats

Predicted Adult Weight

61 lbs

Genetic Age
52 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Alaskan-type Husky
German Shepherd Dog
Siberian Husky
Alaskan Malamute
Unresolved

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Health Summary

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Kiera inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Kiera inherited one copy of the variant we tested

What does this result mean?

This result should not impact Kiera’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Kiera inherited one copy of the variant we tested

Why is this important to your vet?

Kiera has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kiera has this genotype, as ALT is often used as an indicator of liver health and Kiera is likely to have a lower than average resting ALT activity. As such, an increase in Kiera’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in German Shepherd Dogs

Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in German Shepherd Dogs

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in German Shepherd Dogs

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in German Shepherd Dogs

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Alaskan Husky Encephalopathy (SLC19A3)

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Kiera’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Kiera’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Kiera’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Kiera inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Kiera is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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