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Kiara

Biewer Terrier

No bio has been provided yet

Current Location

Edmonton, Alberta, Canada

This dog has been viewed and been given 7 wags

Registration

N/A :

Genetic Breed Result

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Biewer Terrier

The Biewer Terrier is one of the smallest Terriers within the Toy Group, only 7-8 inches tall and typically less than 8 pounds. In spite of the small size, the Biewer is known as a robust and athletic dog.

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Health Summary

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Kiara is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Kiara inherited one copy of the variant we tested

What does this result mean?

Follow-up by our experts indicates that this genetic variant is associated with an increase to Kiara’s risk for developing Intervertebral Disc Disease (Type I).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Kiara have not yet been the focus of research studies, our data indicates that Kiara is likely to be at increased risk.

Impact on Breeding

While further investigation is warranted to determine the clinical presentation and penetrance in Kiara’s breed, we recommend taking this genetic result into account when making breeding decisions.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Kiara inherited one copy of the variant we tested

Why is this important to your vet?

Kiara has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kiara has this genotype, as ALT is often used as an indicator of liver health and Kiara is likely to have a lower than average resting ALT activity. As such, an increase in Kiara’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Biewer Terriers

Primary Lens Luxation (ADAMTS17)

Identified in Biewer Terriers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Kiara’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Kiara’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Kiara’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Kiara inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Kiara is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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