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Keizerin Sissi van de Eenhoornleijn

Stabyhoun

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Registration

N/A : NHSB 3049878

Genetic Breed Result

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Stabyhoun

Renowned for its peaceful disposition, the Stabyhoun is a soft-mouthed retriever, a fine pointer, excellent tracker, and a good watchdog.

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Genetic Stats

Predicted Adult Weight

39 lbs

Genetic Age
50 human years

Based on the date of birth provided

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Health Summary

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Keizerin Sissi van de Eenhoornleijn is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Keizerin Sissi van de Eenhoornleijn inherited both copies of the variant we tested

How to interpret this result

Keizerin Sissi van de Eenhoornleijn has two copies of a variant in the vWF gene and is at risk for developing Type I vWD. Please consult your veterinarian to discuss further diagnostics as well as monitoring and care options for Keizerin Sissi van de Eenhoornleijn.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Degenerative Myelopathy, DM

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Keizerin Sissi van de Eenhoornleijn inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Keizerin Sissi van de Eenhoornleijn is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Clinical Tools

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

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Other Body Features

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Performance

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Through Keizerin Sissi van de Eenhoornleijn’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A16/17/99/100

Map

A1a

Keizerin Sissi van de Eenhoornleijn’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A16/17/99/100

Keizerin Sissi van de Eenhoornleijn’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Newfoundlands, German Shepherd Dogs, and Golden Retrievers.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Keizerin Sissi van de Eenhoornleijn inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Keizerin Sissi van de Eenhoornleijn is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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