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Kaptivate Me Veracini

Koolie

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Genetic Breed Result

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Koolie

These are intelligent, cheerful, and loyal dogs who can make a great addition to a family. The Koolie is not an aggressive breed and is usually comfortable with new people or new surroundings. Koolies are eager to be trained but this doesn't necessarily mean they're easy to train. When starting obedience training, find an instructor who understands how herding dogs work and you will wind up with an excellent companion dog.

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Health Summary

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Kaptivate Me Veracini has one variant that you should let your vet know about.

ALT Activity

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Kaptivate Me Veracini inherited one copy of the variant we tested

Why is this important to your vet?

Kaptivate Me Veracini has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kaptivate Me Veracini has this genotype, as ALT is often used as an indicator of liver health and Kaptivate Me Veracini is likely to have a lower than average resting ALT activity. As such, an increase in Kaptivate Me Veracini’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Koolies

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in Koolies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Koolies

Collie Eye Anomaly (NHEJ1)

Identified in Koolies

Primary Lens Luxation (ADAMTS17)

Identified in Koolies

Cystinuria Type II-A (SLC3A1, Australian Cattle Dog Variant)

Identified in Koolies

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Koolies

Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)

Identified in Koolies

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

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Body Size

Performance

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Through Kaptivate Me Veracini’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B47

Map

B1

Kaptivate Me Veracini’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B47

Kaptivate Me Veracini’s Haplotype

Part of the large B1 haplogroup, we have spotted this haplotype in village dogs in South America, Africa, the Middle East, and South Asia. Among the 8 breeds we have sampled it in, this haplotype occurs most frequently in Newfoundlands, Australian Cattle Dogs, and Pembroke Welsh Corgis.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Kaptivate Me Veracini inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Kaptivate Me Veracini is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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