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Genetic Age
Please note that genetic age is different from calendar age. We can now estimate your dog's calendar age with the Embark Age Test.
The genetic age in this report is an estimation of where your dog is in his or her healthspan.
Dogs age at very different rates due to a number of genetic and environmental factors. Body size is a strong genetic influence: for example, a seven year old Great Dane is at the start of his golden years, but a seven year old Pomeranian is just learning what "slow down" means. Just within this example, you can see that the old "one doggie year = seven human years" adage isn’t going to work.
And yet, knowing your dog’s age is important: it informs what your dog needs as far as food, frequency of veterinary checkups, and exercise. So how do you best determine how old your dog is?
Embark's genetic age feature calculates how old your dog would be if he or she were aging at an average human rate (using humans in the USA as the baseline). So going back to our Dane/Pom example, we'd estimate a seven year old Great Dane at about 80 years old (senior citizen), but a seven year old Pom would be about 42 (adult). Makes way more sense, right?
Personalized genetic age table for Kane
Calendar age
Genetic age
1 year
17 human years
2 years
25 human years
3 years
31 human years
4 years
37 human years
5 years
44 human years
6 years
50 human years
7 years
56 human years
8 years
63 human years
9 years
69 human years
10 years
75 human years
11 years
82 human years
12 years
88 human years
All we need from you is a calendar age. It's okay if this is an estimation: it is just a starting point. We then factor in your dog's breed composition, information at certain genes that affect size, and their inbreeding coefficient to calculate genetic age. Like in humans, in dogs females tend to live longer than males (so an “80 year old” female dog = 80 year old woman). Exercise and diet also play a role in how long your dog will live. Nevertheless, genetic age is the primary risk factor for numerous diseases in dogs, including cancer, kidney disease, osteoarthritis, cataracts, cardiac disease and cognitive decline. It can help you and your vet know what you should feed your dog, what screenings to get, and other aspects of your dog’s care.
Wolfiness score
How wolfy is my dog?
Most dogs have wolfiness scores of 1% or less. We find populations and breeds with higher scores of 2-4% occasionally, and unique dogs with scores of 5% or above more rarely.
What it means for my dog
Your dog’s Wolfiness Score is not a measure of recent dog-wolf hybridization and does not necessarily indicate that your dog has some recent wolf ancestors. (If your dog has recent wolf ancestors, you will see that in the breed mix report.) Instead, the Wolfiness Score is based on the number of ancient genetic variants your dog has in our unique Wolfiness marker panel. Wolfiness scores up to 10% are almost always due to ancient wolf genes that survived many generations, rather than any recent wolf ancestors. These ancient genes may be a few thousand years old, or may even date back to the original domestication event 15,000 years ago. They are bits of a wild past that survive in your dog!
The science
Your dog’s Wolfiness Score is based on hundreds of markers across the genome where dogs (or almost all of them) are the same, but wolves tend to be different. These markers are thought to be related to "domestication gene sweeps" where early dogs were selected for some trait. Scientists have known about “domestication gene sweeps” for years, but do not yet know why each sweep occurred. By finding rare dogs carrying an ancient variant at a certain marker, we can make associations with behavior, size, metabolism, and development that likely caused these unique signatures of “doggyness” in the genome.
Predicted Adult Weight
How does weight matter?
For people with puppies, you probably want to know how big of a crate to buy or just how big to expect your dog to become. But genetic weight is also useful for people with fully grown dogs. Just like with people, overweight and obese dogs suffer reduced length and quality of life. They can develop chronic health conditions and suffer from limited mobility and other issues. While over half of American dogs are overweight or obese, fewer than 15% of their owners realize it. By comparing your dog’s weight to their genetic predicted weight you have one more piece of information about their ideal weight. With this and other pieces of information like weight history and body condition, you and your veterinarian may want to discuss your dog’s diet, exercise, and weight control plan to give your pup the longest, healthiest life possible.
How do we predict weight?
Our test is the only dog DNA test that provides true genetic size not based just on breed ancestry but based on over a dozen genes known to influence a dog’s weight. It uses the most advanced science to determine your dog’s expected weight based on their sex, the combination of these genes, and breed-specific modifiers.
How accurate is the predicted weight?
Unlike in people, healthy weight in dogs is controlled largely by only a few genes. Our algorithm explains over 85% of the variance in healthy adult weight. However, due to a few as-yet-undiscovered genes and genetic interactions that affect size, this algorithm sometimes misses. Occasionally it misses by a fairly large amount especially when a dog has a breed with an unknown size-influencing gene. If we have missed your dog’s weight, your dog may be a scientific discovery waiting to happen! Please be sure to go to the Research tab and complete the Getting to know your dog survey, where you can answer questions about your dog’s current weight and body shape. This information will inform our ongoing research into the genetics of size and weight in dogs.
Haplotypes
Revealing your dog’s ancient heritage
Haplotypes are particular DNA sequences that are inherited entirely from a dog’s mom (maternal) or dad (paternal).
Because they are inherited whole, your dog and his or her mom share the exact same maternal haplotype.
If you have a male dog, your dog and his dad share the exact same paternal haplotype (female dogs don’t inherit paternal haplotypes).
Because most breeds were started with only a few individual dogs, many breeds are dominated by only one or a few haplotypes.
Haplogroups
Revealing your dog’s ancient heritage
Haplogroups are groups of similar DNA sequences (called haplotypes) that are inherited entirely from the mother (maternal) or father (paternal) and don’t get shuffled up like other parts of your dog’s genome.
These groups all originally descend from one male or female wolf, usually one that lived tens of thousands of years ago.
Because they are inherited whole and not shuffled like other DNA, they can be used to trace the ancestral routes that dogs took around the globe en route to your home.
Only male dogs have paternal haplogroups because they are determined by the Y chromosome, which only male dogs have. Both males and females have maternal haplogroups, which come from a part of DNA called the mitochondrial DNA.
Breed analysis
Breed analysis is based on comparing your dog’s DNA with the DNA of dogs from over 350 breeds, types and varieties.
How are Kane's ancestors represented in his DNA?
All dogs are related and share some DNA. Siblings share lots of their DNA (half of it in fact), cousins share a bit less (an eighth), and so on. Because dog breeds are made up of a closed group of dogs, all dogs in that breed share a lot of their DNA, typically about as much as second cousins, though it varies by breed. Different breeds that are closely related share somewhat less DNA, and dogs from very different breeds share even less DNA (but still much more DNA than either dog shares with a cat).
DNA is inherited in pieces, called chromosomes, that are passed along from parent to offspring. Each generation, these chromosomes are broken up and shuffled a bit in a process known as recombination. So, the length of the segments your dog shares with his ancestors decreases with each generation above him: he shares longer segments with his mom than his grandma, longer segments with his grandma than his great-grandma, and so on.
How does Embark know which breeds are in Kane?
We can use the length of segments Kane shares with our reference dogs to see how many generations it has been since they last shared an ancestor. Long segments of DNA that are identical to known purebred dogs tell Embark's scientists that Kane has, without a doubt, a relative from that breed. By testing over 200,000 genetic markers, we build up his genes one DNA segment at a time, to learn the ancestry with great certainty. Other dog DNA tests look at many fewer genetic markers and have to take a guess at breed ancestry based on that.
What does this mean for Kane's looks and behavior?
Look closely and you'll probably find Kane has some physical and/or behavioral resemblance with his ancestor's breeds. The exact similarity depends on which parts of DNA Kane shares with each breed. Some traits associated with each breed are listed in the Breed & Ancestry section of our website. Embark will tell you even more about Kane's traits soon!
P.S. In a small proportion of cases, we find dogs that don’t share segments with other dogs we have tested, indicating the presence of a rare breed that is not part of our reference panel or possibly a true "village dog" without any purebred relatives at all. In these rare cases we contact the owner to find out more and let them know about their unique dog before they get their results. With this in-depth detective work, we are pushing science forward by identifying genetically unique groups of dogs.
“Dogs Like Kane” are based on the percentage of breeds the two dogs have in common. For example, two dogs that are both
27% Golden Retriever and 73% Poodle will have a score of 100%. Sometimes dogs with high scores look alike, and
sometimes they don’t — either way the comparison is based on each dog’s unique DNA.
“Kane was rescued from the dog meat trade in Cambodia, by an organization called Animal Hope & Wellness. He narrowly escaped being boiled alive, but unfortunately did suffer some abuse. He’s been a part of our family for a few months, and seems to be loving his new life here.”
Village dogs are the free-breeding, free-roaming “outside” dogs found around the world living in and around human settlements big and small. They are also known as island dogs, pariah dogs, or free-ranging dogs.
Many village dog populations precede the formation of modern breed dogs.
They make up about 3/4s of the billion or so dogs living on Earth today. They serve as trash cleaners, sentinels, and even sometimes companions while still retaining much of their freedom. Embark’s founders have studied village dogs on six continents since 2007 in their efforts to understand the history, traits, and health of the domestic dog. Through this work they have discovered the origins of the dog in Central Asia, and also identified genetic regions involved in domestication and local adaptation, such as the high altitude adaptation in Himalayan dogs. Embark is the only dog DNA test that includes diverse village dogs from around the world in its breed reference panel.
So what breeds are in my dog?
In a very real sense, Southeast Asian Village Dog is the actual breed of your dog. Village dogs like this descend from separate lines of dogs than the lines that have been bred into standardized breeds like Labradors and Poodles. If you trace the family tree of Kane back, you won’t find any ancestral dogs that are part of any of those standardized breeds.
Village dogs
have lived just about everywhere across the world for thousands of years. Long
before there were any recognized dog breeds, there were village dogs around the fires and trash heaps of early human
villages. Kane is part of this ancient heritage, not descended from a specific
breed, but continuing the ancient lineage of dogs that were our first, best friends.
Embark's co-founders studied Village Dogs on six continents in their efforts to understand the history, traits, and
health of the domestic dog. Through this work, they discovered evidence for the origins of the dog in Central Asia
, and they also identified
genetic regions involved in domestication and local adaptation. As a result, Embark has the largest Village Dog
reference panel of any canine genetics company.
We compared Kane's DNA to a global panel of thousands of village dogs.
This plot highlights regions of the world where Kane's DNA is most similar to
those village dogs. The areas of darkest red reflect the greatest similarity to our village dog panel.
Similarity to village dog groups around the world. Darker red reflects greater similarity.
Kane has one variant that you should let your vet know about.
ALT Activity
Kane inherited one copy of the variant we tested
Why is this important to your vet?
Kane has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kane has this genotype, as ALT is often used as an indicator of liver health and Kane is likely to have a lower than average resting ALT activity. As such, an increase in Kane’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Base Coat Color
Genetic Result:
Ee
Gene:
Melanocortin Receptor 1 (MC1R)
This gene helps determine whether a dog can produce dark (black or brown) hairs or lighter yellow or red hairs. Any result except for ee means that the dog can produce dark hairs. An ee result means that the dog does not produce dark hairs at all, and will have lighter yellow or red hairs over their entire body.
Did You Know?
If a dog has a ee result then the fur’s actual shade can range from a deep copper to yellow/gold to cream - the exact color cannot be predicted solely from this result, and will depend on other genetic factors.
Intensity refers to the concentration of red pigment in the coat. Dogs with more densely concentrated (intense) pigment will be a deeper red, while dogs with less concentrated (dilute) pigment will be tan, yellow, cream, or white. Five locations in the dog genome explain approximately 70% of red pigmentation intensity variation across all dogs. Because the locations we test may not directly cause differences in red pigmentation intensity, we consider this to be a linkage test.
Did You Know?
One of the genes that influences pigment intensity in dogs, TYR, is also responsible for intensity variation in domestic mice, cats, cattle, rabbits, and llamas. In dogs and humans, more genes are involved.
This gene helps determine whether a dog produces brown or black pigments. Dogs with a bb result produce brown pigment instead of black in both their hair and skin, while dogs with a Bb or BB result produce black pigment. Dogs that have ee at the E (Extension) Locus and bb at this B (Brown) Locus are likely to have red or cream coats and brown noses, eye rims, and footpads, which is sometimes referred to as "Dudley Nose" in Labrador Retrievers.
Did You Know?
“Liver” or “chocolate” is the preferred color term for brown in most breeds; in the Doberman Pinscher it is referred to as “red”.
This gene helps determine whether a dog has lighter “diluted” pigment. A dog with a Dd or DD result will not be dilute. A dog with a dd result will have all their black or brown pigment lightened (“diluted”) to gray or light brown, and may lighten red pigment to cream. This affects their fur, skin, and sometimes eye color. The D locus result that we report is determined by three different genetic variants that can work together to cause diluted pigmentation. These are the common d allele, also known as “d1”, and the less common alleles known as “d2” and “d3”. Dogs with two d alleles, regardless of which variant, are typically dilute.
Did You Know?
There are many breed-specific names for these dilute colors, such as “blue”, “charcoal”, “fawn”, “silver”, and “Isabella”. Dilute dogs, especially in certain breeds, have a higher incidence of Color Dilution Alopecia which causes hair loss in some patches.
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color Modifiers
Genetic Result:
KBky
Gene:
Canine Beta-Defensin 103 (CBD103)
This gene helps determine whether the dog has a black coat. Dogs with a kyky result will show a coat color pattern based on the result they have at the A (Agouti) Locus. A KBKB or KBky result means the dog is dominant black, which overrides the fur pattern that would otherwise be determined by the A (Agouti) Locus. These dogs will usually have solid black or brown coats, or if they have ee at the E (Extension) Locus then red/cream coats, regardless of their result at the A (Agouti) Locus. Dogs who test as KBky may be brindle rather than black or brown.
Did You Know?
Even if a dog is “dominant black” several other genes could still impact the dog’s fur and cause other patterns, such as white spotting.
This gene is responsible for causing different coat patterns. It only affects the fur of dogs that do not have ee at the E (Extension) Locus and do have kyky at the K (Dominant Black) Locus. It controls switching between black and red pigment in hair cells, which means that it can cause a dog to have hairs that have sections of black and sections of red/cream, or hairs with different colors on different parts of the dog’s body. Sable or Fawn dogs have a mostly or entirely red coat with some interspersed black hairs. Agouti or Wolf Sable dogs have red hairs with black tips, mostly on their head and back. Black and tan dogs are mostly black or brown with lighter patches on their cheeks, eyebrows, chest, and legs. Recessive black dogs have solid-colored black or brown coats.
Did You Know?
The ASIP gene causes interesting coat patterns in many other species of animals as well as dogs.
In addition to determining if a dog can develop dark fur at all, this gene can give a dog a black “mask” or “widow’s peak,” unless the dog has overriding coat color genetic factors. Dogs with one or two copies of Em in their result will have a mask, which is dark facial fur as seen in the German Shepherd and Pug. Dogs with no Em in their result but one or two copies of Eg will instead have a "widow's peak", which is dark forehead fur.
Did You Know?
The widow’s peak is seen in the Afghan Hound and Borzoi, where it is called either “grizzle” or “domino”.
This gene is responsible for most of the white spotting observed in dogs. Dogs with a result of spsp will have a nearly white coat or large patches of white in their coat. Dogs with a result of Ssp will have more limited white spotting that is breed-dependent. A result of SS means that a dog likely has no white or minimal white in their coat. The S Locus does not explain all white spotting patterns in dogs and other causes are currently being researched. Some dogs may have small amounts of white on the paws, chest, face, or tail regardless of their result at this gene.
Did You Know?
Any dog can have white spotting regardless of coat color. The colored sections of the coat will reflect the dog’s other genetic coat color results.
This gene, along with the M Locus, determines whether a dog will have harlequin patterning. This pattern is recognized in Great Danes and causes dogs to have a white coat with patches of darker pigment. A dog with an Hh result will be harlequin if they are also M*m or M*M* at the M Locus and are not ee at the E locus. Dogs with a result of hh will not be harlequin.
Did You Know?
While many harlequin dogs are white with black patches, some dogs have grey, sable, or brindle patches of color, depending on their genotypes at other coat color genes.
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
Genetic Result:
II
Gene:
RSPO2
This gene is responsible for “furnishings”, which is another name for the mustache, beard, and eyebrows that are characteristic of breeds like the Schnauzer, Scottish Terrier, and Wire Haired Dachshund. A dog with an FF or FI result is likely to have furnishings. A dog with an II result will not have furnishings. We measure this result using a linkage test.
Did You Know?
In breeds that are expected to have furnishings, dogs without furnishings are the exception - this is sometimes called an “improper coat”.
This gene affects hair length in many species, including cats, dogs, mice, and humans. In dogs, an Lh allele confers a long, silky hair coat across many breeds, including Yorkshire Terriers, Cocker Spaniels, and Golden Retrievers. An ShSh or ShLh result is likely to mean a shorter coat, like in the Boxer or the American Staffordshire Terrier. The coat length determined by FGF5, as reported by us, is influenced by four genetic variants that work together to promote long hair.
The most common of these is the Lh1 variant (G/T, CanFam3.1, chr32, g.4509367) and the less common ones are Lh2 (C/T, CanFam3.1, chr32, g.4528639), Lh3 (16bp deletion, CanFam3.1, chr32, g.4528616), and Lh4 (GG insertion, CanFam3.1, chr32, g.4528621). The FGF5_Lh1 variant is found across many dog breeds. The less common variants, FGF5_Lh2 have been found in the Akita, Samoyed, and Siberian Husky, FGF5_Lh3 have been found in the Eurasier, and FGF5_Lh4 have been found in the Afghan Hound, Eurasier, and French Bulldog.
The Lh alleles have a recessive mode of inheritance, meaning that two copies of the Lh alleles are required to have long hair. The presence of two Lh alleles at any of these FGF5 loci is expected to result in long hair. One copy each of Lh1 and Lh2 have been found in Samoyeds, one copy each of Lh1 and Lh3 have been found in Eurasiers and one copy each of Lh1 and Lh4 have been found in Afghan Hounds and Eurasiers.
Did You Know?
In certain breeds, such as Pembroke Welsh Corgi and French Bulldog, the long coat is described as “fluffy.”
This gene affects how much a dog sheds. Dogs with furnishings or wire-haired coats tend to be low shedders regardless of their result for this gene. In other dogs, a CC or CT result indicates heavy or seasonal shedding, like many Labradors and German Shepherd Dogs. Dogs with a TT result tend to be lighter shedders, like Boxers, Shih Tzus and Chihuahuas.
For dogs with long fur, dogs with a TT or CT result will likely have a wavy or curly coat like the coat of Poodles and Bichon Frises. Dogs with a CC result will likely have a straight coat—unless the dog has a "Likely Furnished" result for the Furnishings trait, since this can also make the coat more curly.
Did You Know?
Dogs with short coats may have straight coats, whatever result they have for this gene.
This gene can cause hairlessness over most of the body as well as changes in tooth shape and number. This particular gene occurs in Peruvian Inca Orchid, Xoloitzcuintli (Mexican Hairless), and Chinese Crested; other hairless breeds are due to different genes. Dogs with the NDup result are likely to be hairless while dogs with the NN result are likely to have a normal coat. We measure this result using a linkage test.
Did You Know?
The DupDup result has never been observed, suggesting that dogs with that genotype cannot survive to birth.
This gene causes oculocutaneous albinism (OCA), also known as Doberman Z Factor Albinism. Dogs with a DD result will have OCA. Effects include severely reduced or absent pigment in the eyes, skin, and hair, and sometimes vision problems due to lack of eye pigment (which helps direct and absorb ambient light) and are prone to sunburn. Dogs with a ND result will not be affected, but can pass the mutation on to their offspring. We measure this result using a linkage test.
Did You Know?
This particular mutation can be traced back to a single white Doberman Pinscher born in 1976, and it has only been observed in dogs descended from this individual.
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
Genetic Result:
CC
Gene:
BMP3
This gene affects muzzle length. A dog with a AC or CC result is likely to have a medium-length muzzle like a Staffordshire Terrier or Labrador, or a long muzzle like a Whippet or Collie. A dog with a AA result is likely to have a short muzzle, like an English Bulldog, Pug, or Pekingese.
Did You Know?
At least five different genes affect snout length in dogs, with BMP3 being the only one with a known causal mutation. For example, the muzzle length of some breeds, including the long-snouted Scottish Terrier or the short-snouted Japanese Chin, appear to be caused by other genes. This means your dog may have a long or short snout due to other genetic factors. Embark is working to figure out what these might be.
This is one of the genes that can cause a short bobtail. Most dogs have a CC result and a long tail. Dogs with a CG result are likely to have a bobtail, which is an unusually short or absent tail. This can be seen in many “natural bobtail” breeds including the Pembroke Welsh Corgi, the Australian Shepherd, and the Brittany Spaniel. Dogs with GG genotypes have not been observed, suggesting that dogs with such a result do not survive to birth.
Did You Know?
While certain lineages of Boston Terrier, English Bulldog, Rottweiler, Miniature Schnauzer, Cavalier King Charles Spaniel, and Parson Russell Terrier, and Dobermans are born with a natural bobtail, it is not always caused by this gene. This suggests that other unknown genetic effects can also lead to a natural bobtail.
This is one of the genes that can cause hind dew claws, which are extra, nonfunctional digits located midway between a dog's paw and hock. Dogs with a CT or TT result have about a 50% chance of having hind dewclaws. Hind dew claws can also be caused by other, still unknown, genes. Embark is working to figure those out.
Did You Know?
Hind dew claws are commonly found in certain breeds such as the Saint Bernard.
This gene is associated with blue eyes in Arctic breeds like Siberian Husky as well as tri-colored (non-merle) Australian Shepherds. Dogs with a DupDup or NDup result are more likely to have blue eyes, although some dogs may have only one blue eye or may not have blue eyes at all; nevertheless, they can still pass blue eyes to their offspring. Dogs with a NN result may have blue eyes due to other factors, such as merle or white spotting. We measure this result using a linkage test.
Did You Know?
Embark researchers discovered this gene by studying data from dogs like yours. Who knows what we will be able to discover next? Answer the questions on our research surveys to contribute to future discoveries!
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
Genetic Result:
NN
Gene:
IGF1
This is one of several genes that influence the size of a dog. A result of II for this gene is associated with smaller body size. A result of NN is associated with larger body size.
This is one of several genes that influence the size of a dog. A result of AA for this gene is associated with smaller body size. A result of GG is associated with larger body size.
This is one of several genes that influence the size of a dog. A result of AA for this gene is associated with smaller body size. A result of TT is associated with larger body size.
This is one of several genes that influence the size of a dog. A result of AA for this gene is associated with smaller body size. A result of GG is associated with larger body size.
This is one of several genes that influence the size of a dog. A result of TT for this gene is associated with smaller body size. A result of CC is associated with larger body size.
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Performance
Genetic Result:
GG
Gene:
EPAS1
This gene causes dogs to be especially tolerant of low oxygen environments, such as those found at high elevations. Dogs with a AA or GA result will be less susceptible to "altitude sickness."
Did You Know?
This gene was originally identified in breeds from high altitude areas such as the Tibetan Mastiff.
This gene influences eating behavior. An ND or DD result would predict higher food motivation compared to NN result, increasing the likelihood to eat excessively, have higher body fat percentage, and be more prone to obesity. Read more about the genetics of POMC, and learn how you can contribute to research, in our blog post. We measure this result using a linkage test.
Did You Know?
POMC is actually short for "proopiomelanocortin," and is a large protein that is broken up into several smaller proteins that have biological activity. The smaller proteins generated from POMC control, among other things, distribution of pigment to the hair and skin cells, appetite, and energy expenditure.
Through Kane’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends.
This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.
Haplogroup
A1d
Haplotype
A247
A1d
Kane’s Haplogroup
This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.
A247
Kane’s Haplotype
Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.
The vast majority of Rottweilers have the A1d haplogroup.
Through Kane’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends.
This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.
Haplogroup
A2a
Haplotype
Hc.12
A2a
Kane’s Haplogroup
A2a is a truly ancient lineage. Unlike the recent upstart A1 lineages which found their way from a few popular European males a couple hundred years ago into many dogs in many breeds, A2a shows ancient roots without major recent expansion. It is likely one of the oldest eastern Eurasian male lineages of dogs, where it has existed for thousands of years. Nowadays, it's commonly found in Tibetan Terriers and Chow Chows as well as in Southeastern Asian village dogs. The Chow Chow seems to have been depicted in sculpture over 2,000 years ago, so this is an ancient lineage indeed, and dogs with it have a long and noble pedigree! Males from this lineage have continued to be bred in similar forms and breeds for millennia.
Hc.12
Kane’s Haplotype
Part of the A2a haplogroup, this rare haplotype occurs in Papua New Guinea and Vietnam.
The large-sized Tibetan Mastiff descends from this ancient lineage.
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