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K-And-K’s

Chihuahua

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Place of Birth

Vandalia, Michigan, USA

Current Location

Vandalia, Michigan, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

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Genetic Stats

Predicted Adult Weight

6 lbs

Genetic Age
15 human years

Based on the date of birth provided

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Health Summary

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K-And-K’s has one variant that you should let your vet know about.

ALT Activity

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K-And-K’s inherited one copy of the variant we tested

Why is this important to your vet?

K-And-K’s has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that K-And-K’s has this genotype, as ALT is often used as an indicator of liver health and K-And-K’s is likely to have a lower than average resting ALT activity. As such, an increase in K-And-K’s’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Chihuahuas

Progressive Retinal Atrophy, crd4/cord1 (RPGRIP1)

Identified in Chihuahuas

Neuronal Ceroid Lipofuscinosis 7, NCL 7 (MFSD8, Chihuahua and Chinese Crested Variant)

Identified in Chihuahuas

Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10)

Identified in Chihuahuas

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Chihuahuas

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through K-And-K’s’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

K-And-K’s’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

K-And-K’s’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that K-And-K’s inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since K-And-K’s is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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