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Juneau

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Location
Cedar Park, Texas, USA
From
Dallas Animal Services, North Westmoreland Road, Dallas, TX, USA

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Genetic Breed Result

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50.0% Siberian Husky
18.9% Gray Wolf
17.7% German Shepherd Dog
13.4% Alaskan Malamute
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Genetic Stats


Wolfiness:

42.6 % HIGH

Predicted Adult Weight:

56 lbs

Genetic Age:

52 human years

DNA Breed Origins

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Breed colors:
Siberian Husky
Gray Wolf
German Shepherd Dog
Alaskan Malamute

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Summary

0
AT RISK
0
CARRIER
170
CLEAR
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Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase (ALT) Activity result: Low Normal

Juneau has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Juneau has this genotype, as ALT is often used as an indicator of liver health and Juneau is likely to have a lower than average resting ALT activity. As such, an increase in Juneau’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Juneau did not test positive for any of the genetic diseases that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Juneau’s diagnosis and treatment if he gets sick in the future.

Not A Carrier

Good news! Juneau is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Juneau tested clear for 12 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Juneau.

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Alaskan Malamutes, but not Juneau.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Juneau.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Juneau.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Juneau.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Juneau.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Juneau.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Juneau.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Juneau.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Juneau.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Siberian Huskys, Gray Wolfs, German Shepherd Dogs, Alaskan Malamutes, but not Juneau.

Polyneuropathy, NDRG1 Malamute Variant
(NDRG1 Exon 4)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfunction. Peripheral nerves relay messages between the brain and spinal cord to the res…

Seen in Alaskan Malamutes, but not Juneau.

Other Conditions:
Clear of 158

Juneau is clear of 158 other genetic diseases that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Light colored fur (cream to red)
Brown or Black Pigment
B (Brown) Locus
Likely black colored nose/feet
Color Dilution
D (Dilute) Locus
Dark (non-dilute) skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
No impact on coat color
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
No dark fur anywhere
Saddle Tan
No impact on coat pattern
Merle
M (Merle) Locus
No impact on coat color
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Likely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Likely to have blue eyes or partial blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance

Through Juneau’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

E

Haplotype

E17

Map

E

Juneau’s Haplogroup

Haplogroup E is a very rare maternal line, present primarily in Northern breed dogs and dogs with some level of recent gray wolf ancestry.

E17

Juneau’s Haplotype

The E haplogroup in general is not common. It has been found most frequently in dogs with East Asian breed ancestry.

Some other Embark dogs with this haplotype:

An example of an Akita.

Through Juneau’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A

Haplotype

Hc.1

Map

A

Juneau’s Haplogroup

A is the distant relative of some of the most numerous paternal lineages in the world. Characterized by a single sub-lineage, this is a rare and interesting paternal line! The A line is found most commonly in Siberian Huskies and in Alaskan village dogs. It seems plausible that this paternal lineage diverged within the last 10,000 years from a group arriving with the first Arctic explorers. The recent ancestors of dogs with this lineage actually allowed humans to survive in some of the most forbidding conditions on the face of the earth!

Hc.1

Juneau’s Haplotype

The lone member of the A haplogroup, this haplotype occurs most commonly in Siberian Huskies and village dogs from Alaska.

Some other Embark dogs with this haplotype:

Siberian Huskys are the only breed to have the A haplogroup.