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Jackson

Mixed Breed

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“Senior, male dog, was picked up as a stray on June 24 2019, not chipped or neutered. I adopted him from the animal shelter on August 21st, 2019. He is learning to trust.”

Place of Birth

USA

From

Carson Animal Shelter, West Victoria Street, Gardena, CA, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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American Staffordshire Terrier

American Staffordshire Terriers are powerful but playful dogs that are both loyal and affectionate with their owners.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Basset Hound

Basset Hounds are widely adored, short-legged and long-bodied hunting dogs that are considered great family companions.

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Genetic Stats

Wolfiness

0.3 % LOW

Predicted Adult Weight

53 lbs

Genetic Age
96 human years

Based on the date of birth provided

Dogs Like Jackson

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Discover dogs who share a similar breed mix to Jackson. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Chow Chow
Doberman Pinscher
German Shepherd Dog
Australian Shepherd
American Staffordshire Terrier
Rottweiler
Basset Hound
Supermutt

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Jackson
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Australian Shepherd / Rottweiler mix American Staffordshire Terrier / Basset Hound mix Chow Chow mix Doberman Pinscher / German Shepherd Dog mix Australian Shepherd Rottweiler mix American Staffordshire Terrier Basset Hound mix Chow Chow Chow Chow mix Doberman Pinscher German Shepherd Dog

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Jackson’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Jackson is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Dilated Cardiomyopathy, DCM2

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Jackson inherited one copy of the variant we tested

How to interpret this result

Jackson has one copy of a variant in the TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Jackson shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Jackson.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Jackson inherited both copies of the variant we tested

Why is this important to your vet?

Jackson has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Jackson's ALT activity above their current, healthy, ALT activity. As an increase above Jackson’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Shepherds and German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Thrombopathia

Identified in Basset Hounds

Von Willebrand Disease Type I, Type I vWD

Identified in Doberman Pinschers

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

X-linked Severe Combined Immunodeficiency, X-SCID

Identified in Basset Hounds

Progressive Retinal Atrophy, prcd

Identified in Australian Shepherds

Progressive Retinal Atrophy, crd1

Identified in American Staffordshire Terriers

Progressive Retinal Atrophy, crd2

Identified in American Staffordshire Terriers

Collie Eye Anomaly

Identified in Australian Shepherds

Day Blindness

Identified in German Shepherd Dogs

Canine Multifocal Retinopathy, cmr1

Identified in Australian Shepherds

Hereditary Cataracts

Identified in Australian Shepherds

Urate Kidney & Bladder Stones

Identified in American Staffordshire Terriers, Australian Shepherds, and more

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Staffordshire Terriers

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Shepherds

Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS

Identified in Doberman Pinschers

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Staffordshire Terriers

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Dilated Cardiomyopathy, DCM1

Identified in Doberman Pinschers

Craniomandibular Osteopathy, CMO

Identified in Australian Shepherds

Intervertebral Disc Disease (Type I)

Identified in Basset Hounds

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Jackson’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A381

Map

A1a

Jackson’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A381

Jackson’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Doberman Pinschers, and Dachshunds.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through Jackson’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B

Haplotype

H15.4/5

Map

B

Jackson’s Haplogroup

B is a relatively rare paternal line that has only recently started to expand. The dominant lineage among the ancient Shih Tzu breed, it is also found among Tibetan Spaniels. Outside of these two breeds, B seems to be a particularly common paternal line among the village dogs of India and Southeast Asia, though it is found as far afield as Africa and down into Oceania. Considering that it is particularly diverse in northern India, it could be that this lineage hung out mostly in South Asia after the expansion of domestic dogs from Central Asia. Because it is present in Mongolia as well, it may not be surprising that ancient East Asian dog breeds are also part of this lineage. Alternatively, perhaps males representing this lineage headed north out of southern Eurasia, which eventually gave rise to the Shih Tzu and may have inspired stylistic representations of lions in ancient China!

H15.4/5

Jackson’s Haplotype

Part of the B haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

The B Haplogroup is most commonly found the adorable Shih Tzu breed.

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