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“Izzy”
Izzy

Poodle (Standard)

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“Black Parti Standard Poodle”

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Genetic Breed Result

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“Izzy”
Izzy

Poodle (Standard)
100.0% Poodle (Standard)

Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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Genetic Stats

Predicted Adult Weight

51 lbs

Genetic Age
35 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 6/23/2020 changed handle from "zoe435" to "izzy507"
  • On 6/23/2020 changed name from "Zoe" to "Izzy"

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Izzy’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Izzy has one variant that you should let your vet know about.

ALT Activity

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Izzy inherited one copy of the variant we tested

Why is this important to your vet?

Izzy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Izzy has this genotype, as ALT is often used as an indicator of liver health and Izzy is likely to have a lower than average resting ALT activity. As such, an increase in Izzy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Standard Poodles

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

Additional Genetic Conditions

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Through Izzy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B49

Map

B1

Izzy’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B49

Izzy’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most commonly in Poodles. It’s a rare find!

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Izzy inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Izzy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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