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“Ivy”
Sound of Canna's Hello

Cairn Terrier

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“Fiesty and Fun, a true Cairn-girl!”

Current Location

The Netherlands

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Genetic Breed Result

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Cairn Terrier

The Cairn Terrier is one of the oldest of the terrier breeds, originating in the Scottish Highlands and recognized as one of Scotland's earliest working dogs.

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Genetic Stats

Predicted Adult Weight

14 lbs

Genetic Age
49 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 1/3/2021 changed name from "Ivy" to "Sound of Canna's Hello"

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Health Summary

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Ivy inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Congenital Macrothrombocytopenia

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Ivy inherited one copy of the variant we tested

What does this result mean?

This result should not impact Ivy’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Congenital Macrothrombocytopenia?

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets.

ALT Activity

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Ivy inherited both copies of the variant we tested

Why is this important to your vet?

Ivy has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Ivy's ALT activity above their current, healthy, ALT activity. As an increase above Ivy’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Hemophilia B (F9 Exon 7, Terrier Variant)

Identified in Cairn Terriers

Pyruvate Kinase Deficiency (PKLR Exon 10, Terrier Variant)

Identified in Cairn Terriers

Globoid Cell Leukodystrophy, Krabbe disease (GALC Exon 5, Terrier Variant)

Identified in Cairn Terriers

Craniomandibular Osteopathy, CMO (SLC37A2)

Identified in Cairn Terriers

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Ivy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Sound of Canna's Hello’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Sound of Canna's Hello’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Ivy inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ivy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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