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Ivy

Pembroke Welsh Corgi

“Ivy is the sweetest little girl you will ever meet. Follow us on instagram @CurbysCorgis”

Place of Birth

Coeur d'Alene, ID, USA

Current Location

St. George, Utah, USA

From

Coeur d'Alene, ID, USA

This dog has been viewed and been given 3 wags

Registration

American Kennel Club (AKC):

Genetic Breed Result

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Pembroke Welsh Corgi

The Pembroke Welsh Corgi is a small, energetic, herding dog that is good with families.

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Changes to this dog’s profile
  • On 11/25/2021 changed name from "Annie" to "Ivy"
  • On 11/25/2021 changed name from "Ivy" to "Annie"
Here’s what Ivy’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Ivy’s breed mix.

Breed Reveal Video

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Health Summary

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Ivy is at increased risk for two genetic health conditions.

And inherited one variant that you should learn more about.

Degenerative Myelopathy, DM

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Ivy inherited both copies of the variant we tested

How to interpret this result

Ivy has two copies of a variant in SOD1 and is at risk for developing DM. As previously stated, this variant is incompletely penetrant, so while it predisposes Ivy to developing DM, other genetic and environmental factors will determine whether Ivy ultimately develops the disease. Please consult your veterinarian to discuss further diagnostic, monitoring, and supportive care options for Ivy.'

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Intervertebral Disc Disease (Type I)

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Ivy inherited both copies of the variant we tested

How to interpret this result

Ivy has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Ivy inherited one copy of the variant we tested

Why is this important to your vet?

Ivy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ivy has this genotype, as ALT is often used as an indicator of liver health and Ivy is likely to have a lower than average resting ALT activity. As such, an increase in Ivy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD

Identified in Pembroke Welsh Corgis

X-linked Severe Combined Immunodeficiency, X-SCID

Identified in Pembroke Welsh Corgis

Progressive Retinal Atrophy, rcd3

Identified in Pembroke Welsh Corgis

Exercise-Induced Collapse, EIC

Identified in Pembroke Welsh Corgis

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Ivy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B139

Map

B1

Ivy’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B139

Ivy’s Haplotype

Part of the B1 haplogroup, the B139 haplotype occurs most commonly in Pembroke Welsh Corgis. It's a rare find!

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Ivy inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ivy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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