Issah

Mixed Breed

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This dog has been viewed 1050 times and been given 4 wags

Genetic Breed Result

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Mixed Breed

61.8% Siberian Husky
14.1% American Pit Bull Terrier
13.9% Shetland Sheepdog
10.2% German Shepherd Dog
Siberian Husky Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
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American Pit Bull Terrier American Pit Bull Terrier
The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.
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Shetland Sheepdog Shetland Sheepdog
Shetland Sheepdogs are a lively, smart and athletic herding dogs that also makes a great family pet.
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German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.
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Genetic Stats


Predicted Adult Weight
Genetic Age
36 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Issah’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Siberian Husky
American Pit Bull Terrier
Shetland Sheepdog
German Shepherd Dog

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Siberian Husky Mixed Siberian Husky Siberian Husky American Pit Bull Terrier / German Shepherd Dog mix Shetland Sheepdog / Siberian Husky mix Siberian Husky Siberian Husky Siberian Husky Siberian Husky American Pit Bull Terrier German Shepherd Dog Shetland Sheepdog Siberian Husky

Our algorithms predict this is the most likely family tree to explain Issah’s breed mix, but this family tree may not be the only possible one.

Health Summary

Issah has one variant that you should let your vet know about.

ALT Activity

Issah inherited both copies of the variant we tested

Why is this important to your vet?

Issah has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Issah's ALT activity above their current, healthy, ALT activity. As an increase above Issah’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Multiple Drug Sensitivity (MDR1)

Identified in German Shepherd Dogs and Shetland Sheepdogs

Hemophilia A (F8 Exon 11, Shepherd Variant 1)

Identified in German Shepherd Dogs

Hemophilia A (F8 Exon 1, Shepherd Variant 2)

Identified in German Shepherd Dogs

Von Willebrand Disease Type III, Type III vWD (VWF Exon 7)

Identified in Shetland Sheepdogs

Canine Leukocyte Adhesion Deficiency Type III, CLADIII (FERMT3)

Identified in German Shepherd Dogs

Progressive Retinal Atrophy, CNGA (CNGA1 Exon 9)

Identified in Shetland Sheepdogs

Progressive Retinal Atrophy, crd1 (PDE6B)

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd2 (IQCB1)

Identified in American Pit Bull Terriers

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Collie Eye Anomaly (NHEJ1)

Identified in Shetland Sheepdogs

Day Blindness (CNGA3 Exon 7 German Shepherd Variant)

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in American Pit Bull Terriers and German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3)

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia, NCL4A (ARSG Exon 2)

Identified in American Pit Bull Terriers

GM1 Gangliosidosis (GLB1 Exon 15 Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in German Shepherd Dogs and Shetland Sheepdogs

L-2-Hydroxyglutaricaciduria, L2HGA (L2HGDH)

Identified in American Pit Bull Terriers

Additional Genetic Conditions

Through Issah’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18/19/20/21/27/36/94/109/361

Map

A1b

Issah’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18/19/20/21/27/36/94/109/361

Issah’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in over 25 countries across the world. We have detected this haplotype in lots of breeds, and it occurs most commonly in German Shepherd Dogs, Maltese, English Springer Spaniels, and English Setters.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Issah inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Issah is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.