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Isabelle Rose

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“Belle is such a loving affectionate do. She loves to play with other dogs very gentle with kids.”

Place of Birth

Port Charlotte, FL, USA

Current Location

Port Charlotte, FL, USA

From

Port Charlotte, FL, USA

This dog has been viewed and been given 3 wags

Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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DNA Breed Origins

Breed colors:
Siberian Husky
Pomeranian

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Isabelle Rose
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Siberian Husky / Pomeranian mix Siberian Husky / Pomeranian mix Siberian Husky Pomeranian Siberian Husky Pomeranian Siberian Husky Siberian Husky Pomeranian Pomeranian Siberian Husky Siberian Husky Pomeranian Pomeranian

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Isabelle Rose’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Isabelle Rose inherited three variants that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Isabelle Rose inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Isabelle Rose is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Canine Multifocal Retinopathy, cmr1

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Isabelle Rose inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Isabelle Rose is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Canine Multifocal Retinopathy, cmr1?

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. Dogs with larger lesions can suffer from vision loss. CMR is fairly non-progressive; new lesions will typically stop forming by the time a dog is an adult, and some lesions will even regress with time.

Degenerative Myelopathy, DM

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Isabelle Rose inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Isabelle Rose is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Methemoglobinemia (CYB5R3)

Identified in Pomeranians

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Pomeranians

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Additional Genetic Conditions

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Clinical Tools

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Isabelle Rose’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A29a

Map

A2

Isabelle Rose’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A29a

Isabelle Rose’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in Siberian Huskies, Alaskan Malamutes, Labrador Retrievers, and village dogs from Alaska.

Some other Embark dogs with this haplotype:

Dingos commonly possess this haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Isabelle Rose inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Isabelle Rose is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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