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Intrepid Sue

Australian Kelpie

“Intrepid Sue was adopted from the Elko Animal Shelter in Elko, Nevada. She entered the shelter as a stray approximately August 1, 2014, and was estimated to be 6 months of age. She came to live with me in New York, where she herds sheep, and entertains her foster siblings. She is truly an amazing soul, and my life has been forever enriched because of her.”

Current Location

Freehold, New York, USA

From

Elko, NV, USA

This dog has been viewed and been given 65 wags

Genetic Breed Result

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Australian Kelpie

The Australian Kelpie is a highly intelligent breed of herding dog that likes to work hard. The name for this breed is similar to a creature from Scottish and Irish mythology – a Kelpie is a magical water horse that has ill intentions toward humans, particularly children. In reality, the Australian Kelpie is nothing like this mythological creature – it is friendly and playful, always eager to please its human companions.

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Here’s what Intrepid Sue’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Intrepid Sue’s breed mix.
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Health Summary

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Intrepid Sue inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Intrepid Sue inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Intrepid Sue’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Intrepid Sue is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Intrepid Sue inherited one copy of the variant we tested

Why is this important to your vet?

Intrepid Sue has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Intrepid Sue has this genotype, as ALT is often used as an indicator of liver health and Intrepid Sue is likely to have a lower than average resting ALT activity. As such, an increase in Intrepid Sue’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Kelpies

Trapped Neutrophil Syndrome, TNS

Identified in Australian Kelpies

Progressive Retinal Atrophy, prcd

Identified in Australian Kelpies

Collie Eye Anomaly

Identified in Australian Kelpies

Primary Lens Luxation

Identified in Australian Kelpies

Cystinuria Type II-A

Identified in Australian Kelpies

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Australian Kelpies

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Kelpies

Myotonia Congenita

Identified in Australian Kelpies

Cobalamin Malabsorption

Identified in Australian Kelpies

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Intrepid Sue’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A226

Map

A1e

Intrepid Sue’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A226

Intrepid Sue’s Haplotype

Part of the large A1e haplogroup, we have spotted this haplotype in village dogs in Central and South America and Papua New Guinea. Among the 10 breeds we have detected it in, we see it most frequently in Border Collies, Doberman Pinschers, and Samoyeds.

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Intrepid Sue inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Intrepid Sue is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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