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“Tinker”
CH Indigo Hill Distinctively Sarron

Belgian Shepherd

“Tinker was a good girl. Tinker developed Osteosarcoma in her upper left front leg in April 21'. We had that leg amputated and went through chemotherapy with her for several months. We also sent the diseased limb to Torigen and had a vaccine made from her tumor. We used this vaccine on her after her final Chemo treatment. She responded well. Tinker developed hemangiosarcoma of the Liver in Jan 22, we did a few rounds of chemo for that and ended up putting her to sleep on Apr 18 22.”

Place of Birth

North Carolina, USA

Current Location

Bellbrook, Ohio, USA

From

North Carolina, USA

This dog has been viewed and been given 0 wags

Registration

American Kennel Club (AKC): DN35301004

Genetic Breed Result

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Belgian Sheepdog

The Belgian Sheepdog is one of the four varieties of Belgian Shepherd, though the AKC distinguishes them as their own breed. This active working dog is renowned for its intelligence and drive. If given the opportunity for plenty of physical and mental exercise, the Belgian Sheepdog will astound you with its athleticism and versatility.

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DNA Breed Origins

Breed colors:
Belgian Sheepdog

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Here’s what Tinker’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Tinker’s breed mix.

Breed Reveal Video

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Health Summary

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Tinker has one variant that you should let your vet know about.

ALT Activity

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Tinker inherited one copy of the variant we tested

Why is this important to your vet?

Tinker has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Tinker has this genotype, as ALT is often used as an indicator of liver health and Tinker is likely to have a lower than average resting ALT activity. As such, an increase in Tinker’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in Belgian Sheepdogs and Belgian Shepherds

Spongy Degeneration with Cerebellar Ataxia 1 (KCNJ10)

Identified in Belgian Sheepdogs and Belgian Shepherds

Spongy Degeneration with Cerebellar Ataxia 2 (ATP1B2)

Identified in Belgian Sheepdogs and Belgian Shepherds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Tinker’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A382

Map

A1a

Indigo Hill Distinctively Sarron’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A382

Indigo Hill Distinctively Sarron’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Labrador Retrievers, Golden Retrievers, and Chesapeake Bay Retrievers.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Tinker inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Tinker is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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