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“Chloe”
Huiterty's Chloe Belladonna's Hot Cake

Mixed Ancestry

  • Chloe, a Poodle (Small) and Cocker Spaniel mix tested with EmbarkVet.com Chloe, a Poodle (Small) and Cocker Spaniel mix tested with EmbarkVet.com

“Chloe is a F2 cockapoo from our F1 CP Bella and F2 CP Gambit. We cant wait for her embark "Reveal" .”

Place of Birth

Cañon City, Colorado, USA

Current Location

Cañon City, Colorado, USA

From

Cañon City, Colorado, USA

This dog has been viewed and been given 10 wags

Registration

N/A : HHEAD20CP189

Genetic Breed Result

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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English Cocker Spaniel

English Cockers are a medium-size dog with long ears and a happy disposition. The name Cocker comes from their use to hunt woodcock in England, although English Cockers have been used to hunt many other types of birds as well. They make great companion dogs for people who can give them the exercise they need.

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English Cocker Spaniel (Working Type)

English Cockers are a medium-size dog with long ears and a happy disposition. The name Cocker comes from their use to hunt woodcock in England, although English Cockers have been used to hunt many other types of birds as well. They make great companion dogs for people who can give them the exercise they need. A field-bred cocker spaniel is first and foremost an upland flushing dog, bred for skills like hup, retrieve to hand, quarter, follow hand signals, and steady.

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DNA Breed Origins

Breed colors:
Poodle (Small)
Cocker Spaniel
English Cocker Spaniel
English Cocker Spaniel (Working Type)

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Health Summary

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Chloe is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Chloe inherited both copies of the variant we tested

How to interpret this result

Chloe has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Acral Mutilation Syndrome

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Chloe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Chloe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Chloe is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Acral Mutilation Syndrome?

HSAN is a rare condition affecting the dog's ability to feel pain.

ALT Activity

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Chloe inherited one copy of the variant we tested

Why is this important to your vet?

Chloe has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Chloe has this genotype, as ALT is often used as an indicator of liver health and Chloe is likely to have a lower than average resting ALT activity. As such, an increase in Chloe’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Small Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Cocker Spaniels, English Cocker Spaniels, and more

Familial Nephropathy (COL4A4 Exon 3, Cocker Spaniel Variant)

Identified in Cocker Spaniels, English Cocker Spaniels, and more

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant)

Identified in Cocker Spaniels, English Cocker Spaniels, and more

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Small Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Small Poodles

Exercise-Induced Collapse, EIC (DNM1)

Identified in Cocker Spaniels, English Cocker Spaniels, and more

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Small Poodles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Chloe’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A437

Map

A1e

Huiterty's Chloe Belladonna's Hot Cake’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A437

Huiterty's Chloe Belladonna's Hot Cake’s Haplotype

Part of the A1e haplogroup, the A437 haplotype occurs most commonly in Brussels Griffons, Armenian Gamprs and Russell-type Terriers. We've also spotted it in East Asian Village Dogs, Middle Eastern Village Dogs and American Village Dogs.

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Chloe inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Chloe is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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