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“Pepe”
Howling Spirits Super Pepe

Mixed Ancestry

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Current Location

Phelps, Wisconsin, USA

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Registration

American Kennel Club (AKC): WS39444906

Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Alaskan-type Husky

The Alaskan Husky is all athlete. These dogs have a wide variety of appearances because they are bred for performance and behavior rather than looks. In fact, they've been specifically bred to pull sleds for hundreds of years. In temperament, they tend to be similar to the Siberian Husky.

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DNA Breed Origins

Breed colors:
Siberian Husky
Alaskan-type Husky

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Health Summary

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Pepe has one variant that you should let your vet know about.

ALT Activity

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Pepe inherited one copy of the variant we tested

Why is this important to your vet?

Pepe has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Pepe has this genotype, as ALT is often used as an indicator of liver health and Pepe is likely to have a lower than average resting ALT activity. As such, an increase in Pepe’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Siberian Huskies

Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant)

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Alaskan Husky Encephalopathy (SLC19A3)

Degenerative Myelopathy, DM (SOD1A)

Identified in Siberian Huskies

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Pepe’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

E

Haplotype

E40

Map

E

Howling Spirits Super Pepe’s Haplogroup

Haplogroup E is a very rare maternal line, present primarily in Northern breed dogs and dogs with some level of recent gray wolf ancestry.

E40

Howling Spirits Super Pepe’s Haplotype

Part of the E haplogroup, this haplotype occurs most frequently in mixed breed dogs.

An example of an Akita.

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Through Pepe’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A

Haplotype

Hc.1

Map

A

Howling Spirits Super Pepe’s Haplogroup

A is the distant relative of some of the most numerous paternal lineages in the world. Characterized by a single sub-lineage, this is a rare and interesting paternal line! The A line is found most commonly in Siberian Huskies and in Alaskan village dogs. It seems plausible that this paternal lineage diverged within the last 10,000 years from a group arriving with the first Arctic explorers. The recent ancestors of dogs with this lineage actually allowed humans to survive in some of the most forbidding conditions on the face of the earth!

Hc.1

Howling Spirits Super Pepe’s Haplotype

The lone member of the A haplogroup, this haplotype occurs most commonly in Siberian Huskies and village dogs from Alaska.

Siberian Huskys are the only breed to have the A haplogroup.

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