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Hey Jude do Jardim Imbui

Terrier Brasileiro

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“She adopts all the puppys that she can find”

Place of Birth

Niterói, RJ, Brasil

Current Location

Rio de Janeiro, Rio de Janeiro, Brasil

From

Niterói, RJ, Brasil

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Registration

Canadian Bully Kennel Club (CBKC): RJB/17/03655

Genetic Breed Result

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Terrier Brasileiro

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Health Summary

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Hey Jude do Jardim Imbui is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Canine Multifocal Retinopathy, cmr1

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Hey Jude do Jardim Imbui inherited both copies of the variant we tested

How to interpret this result

Hey Jude do Jardim Imbui has two copies of a variant in the BEST1 gene and is at risk for developing CMR. Please consult your veterinarian regarding an ophthalmologic exam and other diagnostics for Hey Jude do Jardim Imbui.

What is Canine Multifocal Retinopathy, cmr1?

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. Dogs with larger lesions can suffer from vision loss. CMR is fairly non-progressive; new lesions will typically stop forming by the time a dog is an adult, and some lesions will even regress with time.

Degenerative Myelopathy, DM

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Hey Jude do Jardim Imbui inherited both copies of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Hey Jude do Jardim Imbui will develop this condition.

Scientific Basis

Dogs with Hey Jude do Jardim Imbui’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Hey Jude do Jardim Imbui developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Hey Jude do Jardim Imbui inherited both copies of the variant we tested

Why is this important to your vet?

Hey Jude do Jardim Imbui has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Hey Jude do Jardim Imbui's ALT activity above their current, healthy, ALT activity. As an increase above Hey Jude do Jardim Imbui’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 5, Terrier Brasileiro Variant)

Identified in Terrier Brasileiros

Additional Genetic Conditions

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Traits

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Coat Color

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Through Hey Jude do Jardim Imbui’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C42/54/55

Map

C2

Hey Jude do Jardim Imbui’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C42/54/55

Hey Jude do Jardim Imbui’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Hey Jude do Jardim Imbui inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Hey Jude do Jardim Imbui is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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