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“Chase”
Hatch Chase Thaddeus Atom

Bichonpoo

“Spunky and loves to cuddle. Great temperament and manners”

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Genetic Breed Result

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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Bichon Frise

The Bichon Frise is a hypoallergenic, fluffy, white companion breed with a charismatic, cheerful temperament. Known for their clownish antics, the Bichon Frise can put a smile on anyone's face.

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DNA Breed Origins

Breed colors:
Poodle (Small)
Bichon Frise

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Changes to this dog’s profile
  • On 4/4/2018 changed handle from "hatchchasethaddeusatom" to "hatchchase2"
Here’s what Chase’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Chase’s breed mix.
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Health Summary

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Chase is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Chase inherited both copies of the variant we tested

How to interpret this result

Chase has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Von Willebrand Disease Type II, Type II vWD

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Chase inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Chase’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Chase is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Von Willebrand Disease Type II, Type II vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. There are multiple types of vWD, some common and some rare, with marked differences in severity. Please inform your veterinarian of your dog’s vWD status.

ALT Activity

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Chase inherited one copy of the variant we tested

Why is this important to your vet?

Chase has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Chase has this genotype, as ALT is often used as an indicator of liver health and Chase is likely to have a lower than average resting ALT activity. As such, an increase in Chase’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Small Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Small Poodles

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Small Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Small Poodles

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Small Poodles

Additional Genetic Conditions

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Through Chase’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247

Map

A1d

Hatch Chase Thaddeus Atom’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247

Hatch Chase Thaddeus Atom’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.

The vast majority of Rottweilers have the A1d haplogroup.

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Through Chase’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.1

Map

A1a

Hatch Chase Thaddeus Atom’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.1

Hatch Chase Thaddeus Atom’s Haplotype

Part of the large A1a haplogroup, this common haplotype occurs in village dogs all over the world (outside of Asia), with many occurring in Central and South America. We have found this haplotype frequently in Bernese Mountain Dogs, Australian Shepherds, and Boston Terriers.

Dogs with A1a lineage travelled during European Colonial times.

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