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Harper

Mixed Ancestry

“Harper lives the good life in Lincoln Park Chicago (but she’d never admit it to you, preferring instead to keep a straight face) which is a long way from her Alabama roots. She loves everyone she meets.”

Instagram tag
@hellofromharper

Place of Birth

Alabama, USA

Current Location

Chicago, Illinois, USA

From

The Anti-Cruelty Society, West Grand Avenue, Chicago, IL, USA

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Mountain Cur

Mountain Curs are an American breed of treeing hound. Developed in the South—particularly Kentucky, Virginia, and Tennessee—Mountain Curs are an all-American breed that has been prized for years as excellent hunting companions and loyal pets.

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Redbone Coonhound

The Redbone Coonhound is a versatile hunting dog with a flashy red coat. These guys make wonderful companions and are completely devoted to their owners. This American breed has quite the voice and isn't afraid to wake the neighbors!

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American Bulldog

American bulldogs are enjoying a healthy increase in popularity, either as a working/protector dog or as a family pet. All over the world, they are used variously as "hog dogs" (catching escaped pigs or hunting razorbacks), as cattle drovers and as working or sport K-9s. American Bulldogs also successfully compete in several dog sports such as dog obedience, Iron Dog competition and weight pulling.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Basset Hound

Basset Hounds are widely adored, short-legged and long-bodied hunting dogs that are considered great family companions.

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Dogs Like Harper

Venn diagram

Discover dogs who share a similar breed mix to Harper. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Mountain Cur
Redbone Coonhound
American Bulldog
Boxer
Basset Hound

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Here’s what Harper’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Harper’s breed mix.
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Health Summary

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Harper inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Harper inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Harper’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Harper is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Harper inherited one copy of the variant we tested

Why is this important to your vet?

Harper has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Harper has this genotype, as ALT is often used as an indicator of liver health and Harper is likely to have a lower than average resting ALT activity. As such, an increase in Harper’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Hemophilia A

Identified in Boxers

Thrombopathia

Identified in Basset Hounds

X-linked Severe Combined Immunodeficiency, X-SCID

Identified in Basset Hounds

Canine Multifocal Retinopathy, cmr1

Identified in American Bulldogs

Urate Kidney & Bladder Stones

Identified in American Bulldogs

Neuronal Ceroid Lipofuscinosis 10, NCL 10

Identified in American Bulldogs

Ichthyosis

Identified in American Bulldogs

Intervertebral Disc Disease (Type I)

Identified in Basset Hounds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Harper’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Harper’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Harper’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Harper inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Harper is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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