What is Embark?

Harley

Mixed Breed

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“I'm a ruff and tumble girl who enjoys nothing more than wrestling and getting dirty. I even kicked parvo's butt as a puppy! But I have a sweet side too and in the privacy of my own home (where the other dogs can't see me - gotta keep my street cred!) I am a cuddler.”

Instagram tag
@harley_the_embarkdog

Place of birth
Texas, USA
Location
Boston, Massachusetts, USA
From
Austin Pets Alive!, West Cesar Chavez Street, Austin, TX, USA

This dog has been viewed 7860 times and been given 207 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

50.0% Staffordshire Terrier
23.7% Golden Retriever
14.5% Australian Cattle Dog
11.8% Great Pyrenees
Staffordshire Terrier Staffordshire Terrier
Staffordshire Terriers, sometimes referred to as "pit bull" type, are intelligent and trainable dogs. They can have a lot of energy and are often great canine athletes!
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Golden Retriever Golden Retriever
Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.
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Australian Cattle Dog Australian Cattle Dog
A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.
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Great Pyrenees Great Pyrenees
The Great Pyrenees is an exceptionally loving dog whose primary function is to protect sheep, goats, livestock, people, children, grass, flowers, the moon, lawn furniture, and any real or imaginary predators that may intrude on your personal space. They have a strong build and an amazing thick white coat that exudes elegance and majesty. They make a great family dog because of their intelligence and steady temperament.
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Genetic Stats

Wolfiness: 0.8 % MEDIUM Learn More
Predicted Adult Weight: 56 lbs Learn More
Genetic Age: 32 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Harley’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Staffordshire Terrier
Golden Retriever
Australian Cattle Dog
Great Pyrenees

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Harley’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
2
CARRIER
156
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Harley has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Harley has t…

Not At Risk

Good news! Harley did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Harley does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Harley’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Carrier for 2 genetic conditions

Harley is a carrier for 2 of the genetic diseases that Embark tests for.
What does Carrier mean?

Harley has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Harley ever has children.

Condition List

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Collie Eye Anomaly, Choroidal Hypoplasia
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Common Conditions

Good news! Harley tested clear for 22 genetic conditions that are common in her breed mix.
Condition List

Glanzmann's Thrombasthenia Type I
(ITGA2B Exon 13)
Blood

A disease of defective platelet aggregation, this causes affected dogs to bleed excessively in response to mild tissue trauma. Platelets are the first responders to tissu…

Seen in Great Pyreneess, but not Harley.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Golden Retrievers, Australian Cattle Dogs, but not Harley.

Golden Retriever Progressive Retinal Atrophy 1
(SLC4A3)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Golden Retrievers, but not Harley.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Golden Retrievers, but not Harley.

Progressive Retinal Atrophy - crd1
(PDE6B)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Staffordshire Terriers, but not Harley.

Progressive Retinal Atrophy - crd2
(IQCB1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Staffordshire Terriers, but not Harley.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. CMR is typically only identified when a vet examines the eye which, in dogs with C…

Seen in Great Pyreneess, but not Harley.

Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts
(HSF4 Exon 9 Boston Terrier Variant)
Eyes

One of the leading causes of blindness in dogs (and humans!), cataracts are a progressive disease of the lens that causes functional blindness, but can be surgically corr…

Seen in Staffordshire Terriers, but not Harley.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Australian Cattle Dogs, but not Harley.

Cystinuria Type II-A
(SLC3A1)
Kidney and Bladder

A disease of cystine accumulation, affected dogs are prone to developing cystine kidney and bladder stones, which if caught early can be managed with dietary changes, inc…

Seen in Australian Cattle Dogs, but not Harley.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in Staffordshire Terriers, but not Harley.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia - NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Staffordshire Terriers, but not Harley.

Neuronal Ceroid Lipofuscinosis 1
(CLN5 Border Collie Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Harley.

Neuronal Ceroid Lipofuscinosis
(CLN8)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Harley.

Neuronal Ceroid Lipofuscinosis
(CLN5 Golden Retriever Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Golden Retrievers, but not Harley.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Staffordshire Terriers, Golden Retrievers, Australian Cattle Dogs, Great Pyreneess, but not Harley.

L-2-Hydroxyglutaricaciduria
(L2HGDH)
Brain and Spinal Cord

Currently there is no definitive treatment for L2HGA; rather, the condition is managed with anti-seizure and anti-anxiety medications. A rare metabolic disorder, this can…

Seen in Staffordshire Terriers, but not Harley.

Muscular Dystrophy
Muscular Dystrophy (DMD Golden Retriever Variant)
Muscular

Characterized by non-painful muscle weakness and wasting, early diagnosis and supportive treatment can slow the pace of this progressive muscle disease. All known mutatio…

Seen in Golden Retrievers, but not Harley.

Myotonia Congenita
(CLCN1 Exon 23)
Muscular

This condition is characterized by prolonged muscle contraction and stiffness that usually resolves with normal exercise, though physical therapy can be beneficial. The g…

Seen in Australian Cattle Dogs, but not Harley.

Dystrophic Epidermolysis Bullosa
(COL7A1)
Skin & Connective Tissues

This skin disorder gives affected dogs skin that stretches and tears easily; affected dogs must be monitored closely and treated promptly for any injuries. It arises from…

Seen in Golden Retrievers, but not Harley.

Ichthyosis
(PNPLA1)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin (“ichthys” is Greek for “fish”) that affected dogs display on their noses, paw pads, and …

Seen in Golden Retrievers, but not Harley.

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A1)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Seen in Golden Retrievers, but not Harley.

Other Conditions: Clear of 134

Harley is clear of 134 other genetic diseases that Embark tests for.

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Family tree

Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
EmE or Eme
K Locus (Dominant Black)
KBKB
A Locus (Agouti, Sable)
aya or ayat
D Locus (Dilute, Blue, Fawn)
Dd
B Locus (Brown, Chocolate, Liver, Red, Dudley)
BB

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CT
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N
Oculocutaneous Albinism Type 2 - OCA2, Doberman Z Factor Albinism (SLC45A2)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NI
Body Size - IGF1R
GG
Body Size - STC2
TA
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Harley’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Harley’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Harley’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Family tree

Health

Traits

Paternal Haplotype

This 'Paternal Haplotype' tab is for deep ancestral lineage going back thousands of years.

For recent ancestry—"What breeds did my dog inherit from her mom and dad?"—please refer to the Breed, Family Tree, or Summary tab.

The Paternal Haplotype refers to a dog’s deep ancestral lineage stretching back thousands of years, before there were any distinct breeds of dog. We determine the Paternal Haplotype by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Harley is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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Family tree

Health

Traits

Maternal Haplotype