Venn diagram

Compare your dogs to Zia Select one to begin:

“Zia”
CH. Guichon's Knockout Zip It!

Chihuahua

No bio has been provided yet

Place of Birth

Purcellville, VA, USA

Current Location

Bayfield, CO, USA

From

Purcellville, VA, USA

This dog has been viewed and been given 0 wags

Registration

American Kennel Club (AKC): TS46888703

Genetic Breed Result

Loading...

Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

Learn More

Loading...

Start a conversation! Message this dog’s owner.

Loading...

Explore

Changes to this dog’s profile
  • On 3/18/2022 changed name from "CH Guichon's Knockout Zip It!" to "CH. Guichon's Knockout Zip It!"
  • On 9/9/2021 changed name from "Guichon's Knockout Zip It!" to "CH Guichon's Knockout Zip It!"

Health Summary

warn icon

Zia inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

warn icon

Zia inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Zia’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Zia is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

warn icon

Zia inherited one copy of the variant we tested

Why is this important to your vet?

Zia has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Zia has this genotype, as ALT is often used as an indicator of liver health and Zia is likely to have a lower than average resting ALT activity. As such, an increase in Zia’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

good icon

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Chihuahuas

Neuronal Ceroid Lipofuscinosis 7, NCL 7 (MFSD8, Chihuahua and Chinese Crested Variant)

Identified in Chihuahuas

Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10)

Identified in Chihuahuas

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Chihuahuas

Additional Genetic Conditions

good icon

Explore

Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

Loading...

Explore

Through Zia’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247

Map

A1d

CH. Guichon's Knockout Zip It!’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247

CH. Guichon's Knockout Zip It!’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.

The vast majority of Rottweilers have the A1d haplogroup.

Loading...

Explore

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Zia inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Zia is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

Loading...

Explore