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Graham

Mixed Breed

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“R.I.P. my friend. Due to an unknown growth in his abdomen, Graham's gallbladder ruptured and he passed away on August 21, 2021 at the age of 11 years, 2 months. He is missed every day. He's loud and bossy and he's my best little bud. I call him my little Cajun Tot because he's the color of a...um...cajun tot.”

Place of Birth

California, USA

Current Location

Tigard, Oregon, USA

From

Hillsboro, Oregon, USA

This dog has been viewed and been given 8 wags

Genetic Breed Result

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

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Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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Lhasa Apso

An independent breed, the Lhasa's goal in life is not necessarily to please their master. The Lhasa Apso is a small, hardy breed with a beautiful cloak of hair that parts down the back from head to tail. Their temperament is unique: joyful and mischievous, dignified and aloof. Popular in the show ring, the breed also excels at activities that provide constant challenges, such as agility.

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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Miniature Pinscher

The Miniature Pinscher is a small breed of dog originating from Germany. The breed's earliest ancestors may have included the German Pinscher mixed with Italian greyhounds and dachshunds.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Genetic Stats

Wolfiness

1.5 % HIGH

Predicted Adult Weight

42 lbs

Genetic Age
85 human years

Based on the date of birth provided

Dogs Like Graham

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Discover dogs who share a similar breed mix to Graham. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
American Pit Bull Terrier
Chihuahua
Australian Shepherd
Lhasa Apso
Poodle (Small)
Miniature Pinscher
German Shepherd Dog

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Graham
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Australian Shepherd / German Shepherd Dog mix Lhasa Apso / Poodle (Small) mix American Pit Bull Terrier mix Chihuahua / Miniature Pinscher mix Australian Shepherd German Shepherd Dog mix Lhasa Apso Poodle (Small) American Pit Bull Terrier American Pit Bull Terrier mix Chihuahua Miniature Pinscher

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Graham’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Graham is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Degenerative Myelopathy, DM

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Graham inherited both copies of the variant we tested

How to interpret this result

Graham has two copies of a variant in SOD1 and is at risk for developing DM. As previously stated, this variant is incompletely penetrant, so while it predisposes Graham to developing DM, other genetic and environmental factors will determine whether Graham ultimately develops the disease. Please consult your veterinarian to discuss further diagnostic, monitoring, and supportive care options for Graham.'

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Graham inherited one copy of the variant we tested

Why is this important to your vet?

Graham has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Graham has this genotype, as ALT is often used as an indicator of liver health and Graham is likely to have a lower than average resting ALT activity. As such, an increase in Graham’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Shepherds and German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Von Willebrand Disease Type I, Type I vWD

Identified in Small Poodles

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Platelet Factor X Receptor Deficiency, Scott Syndrome

Identified in German Shepherd Dogs

Progressive Retinal Atrophy, prcd

Identified in Australian Shepherds, Chihuahuas, and more

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Lhasa Apsos

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Chihuahuas

Collie Eye Anomaly

Identified in Australian Shepherds

Day Blindness

Identified in German Shepherd Dogs

Canine Multifocal Retinopathy, cmr1

Identified in Australian Shepherds

Hereditary Cataracts

Identified in Australian Shepherds

Cystinuria Type II-B

Identified in Miniature Pinschers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers, Australian Shepherds, and more

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 7, NCL 7

Identified in Chihuahuas

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Shepherds

GM2 Gangliosidosis

Identified in Small Poodles

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Chihuahuas

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Neonatal Encephalopathy with Seizures, NEWS

Identified in Small Poodles

Oculocutaneous Albinism, OCA

Identified in Lhasa Apsos

Osteochondrodysplasia

Identified in Small Poodles

Craniomandibular Osteopathy, CMO

Identified in Australian Shepherds

Intervertebral Disc Disease (Type I)

Identified in Chihuahuas and Small Poodles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Graham’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A29a

Map

A2

Graham’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A29a

Graham’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in Siberian Huskies, Alaskan Malamutes, Labrador Retrievers, and village dogs from Alaska.

Some other Embark dogs with this haplotype:

Dingos commonly possess this haplogroup.

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Through Graham’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.23

Map

A1a

Graham’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.23

Graham’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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