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“Cali”
GN's Californication

Boxer

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Registration

American Kennel Club (AKC): WS83797202

Genetic Breed Result

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Changes to this dog’s profile
  • On 8/28/2024 changed name from "GN's Margarita" to "GN's Californication"

Health Summary

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Cali inherited one variant that you should learn more about.

Copper Toxicosis (Accumulating)

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Cali inherited both copies of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Cali will develop Copper Toxicosis (Accumulating).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Cali's breed have been studied to know whether or not this variant will increase Cali's risk of developing this disease.

Impact on Breeding

Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Copper Toxicosis (Accumulating) in your breeding program and related dogs.

What is Copper Toxicosis (Accumulating)?

Copper toxicosis is a condition in which affected dogs have difficulty excreting excess copper from their liver. The liver accumulates more copper until it eventually begins failing. Multiple genetic and environmental factors contribute to the development of this condition.

Breed-Relevant Genetic Conditions

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Hemophilia A (F8 Exon 10, Boxer Variant)

Identified in Boxers

Degenerative Myelopathy, DM (SOD1A)

Identified in Boxers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

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Through Cali’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A602

Map

A1d

GN's Californication’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A602

GN's Californication’s Haplotype

Part of the A1d haplogroup, the A602 haplotype occurs most commonly in Boxers. It's a rare find!

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Cali inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Cali is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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