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Giselle

Schnoodle (9.3% unresolved)

“Gisele likes to hang out with the horses at the barn. She likes to eat horse feed, loves horse treats and will give the horses kisses sometimes.”

Place of Birth

Summerfield, Florida, USA

Current Location

Archer, Florida, USA

From

Reddick, Florida, USA

This dog has been viewed and been given 0 wags

Registration

N/A :

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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Giant Schnauzer

The Giant Schaunzer is a rambunctious fellow with a keen guard dog instinct. These dogs hail from Germany, where they most recently have served as police dogs. With a strong willed owner and proper socialization, these giants can make great companions.

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Start a conversation! Message this dog’s owner.

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DNA Breed Origins

Breed colors:
Poodle (Standard)
Giant Schnauzer
Unresolved

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Health Summary

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Giselle is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Von Willebrand Disease Type I, Type I vWD

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Giselle inherited one copy of the variant we tested

How to interpret this result

Giselle has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Collie Eye Anomaly

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Giselle inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Giselle’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Giselle is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Collie Eye Anomaly?

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia. The choroid anchors the retina to the underlying structures and supplies it with oxygen and nourishment. CEA is a developmental disease of the choroid.

ALT Activity

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Giselle inherited one copy of the variant we tested

Why is this important to your vet?

Giselle has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Giselle has this genotype, as ALT is often used as an indicator of liver health and Giselle is likely to have a lower than average resting ALT activity. As such, an increase in Giselle’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency (F7 Exon 5)

Identified in Giant Schnauzers

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Giant Schnauzers and Standard Poodles

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Giant Schnauzers

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Standard Poodles

Fetal-Onset Neonatal Neuroaxonal Dystrophy (MFN2, Giant Schnauzer Variant)

Identified in Giant Schnauzers

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Dilated Cardiomyopathy, DCM (RBM20, Schnauzer Variant)

Identified in Giant Schnauzers

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

β-Mannosidosis (MANBA Exon 16, Mixed-Breed Variant)

Identified in Mixed-breed dogs

Progressive Retinal Atrophy 5, PRA5 (NECAP1 Exon 6, Giant Schnauzer Variant)

Identified in Giant Schnauzers

Xanthine Urolithiasis (XDH, Mixed Breed Variant)

Identified in Mixed-breed dogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Giselle’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C42/54/55

Map

C2

Giselle’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C42/54/55

Giselle’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

You can often find his haplogroup in the lovable English Bulldog.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Giselle inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Giselle is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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