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Ginger

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“Long Hair Red EE Dachshund”

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Genetic Stats

Predicted Adult Weight

14 lbs

Genetic Age
26 human years

Based on the date of birth provided

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Health Summary

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Ginger is at increased risk for two genetic health conditions.

Progressive Retinal Atrophy, crd4/cord1

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Ginger inherited both copies of the variant we tested

How to interpret this result

Ginger has two copies of a mutated allele at the RPGRIP1 gene and is at high risk for developing Cone Rod Dystrophy PRA. Please consult with your veterinarian to develop a diagnostic and monitoring plan for Ginger.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

Intervertebral Disc Disease (Type I)

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Ginger inherited both copies of the variant we tested

How to interpret this result

Ginger has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Breed-Relevant Genetic Conditions

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Mucopolysaccharidosis Type IIIA, Sanfilippo Syndrome Type A, MPS IIIA (SGSH Exon 6, Dachshund Variant)

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 1, NCL 1 (PPT1 Exon 8, Dachshund Variant 1)

Identified in Dachshunds

Neuronal Ceroid Lipofuscinosis 2, NCL 2 (TPP1 Exon 4, Dachshund Variant 2)

Identified in Dachshunds

Narcolepsy (HCRTR2 Exon 1, Dachshund Variant)

Identified in Dachshunds

Osteogenesis Imperfecta (SERPINH1, Dachshund Variant)

Identified in Dachshunds

Additional Genetic Conditions

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Clinical Tools

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

E Locus (MC1R)
No dark hairs anywhere (ee)
K Locus (CBD103)
Not expressed (kyky)
Intensity Loci LINKAGE
Any pigmented hair likely yellow or tan (Intermediate Red Pigmentation)
A Locus (ASIP)
Not expressed (atat)
D Locus (MLPH)
Not expressed (DD)
B Locus (TYRP1)
Likely black colored nose/feet (Bb)
Saddle Tan (RALY)
Not expressed (NI)
S Locus (MITF)
Likely solid colored, but may have small amounts of white (Ssp)
M Locus (PMEL)
No merle alleles (mm)
H Locus (Harlequin)
No harlequin alleles (hh)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely long coat (TT)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Likely to have hind dew claws (CT)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Smaller (II)
Body Size (IGFR1)
Smaller (AA)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Smaller (AA)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)
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