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George

Mixed Breed

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Place of Birth

Ontario, Canada

Current Location

Ontario, Canada

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Genetic Breed Result

Boston Terrier

Boston Terriers are lively, intelligent and friendly. Although a small dog, they are strong and sturdy. Owners of this breed find them to be As the breed's name implies, the Boston Terrier originated in the city of Boston in the late 19th century. They're sometimes referred to be their nickname of the "American gentleman" because of their tuxedo-like coat.

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Great Dane

Great Danes are large lovable dogs that need exercise and space. Many Great Danes are "leaners"-- they lean against their people to be closer to them, seemingly oblivious to their size!

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Genetic Stats

Wolfiness

0.9 % MEDIUM

Predicted Adult Weight

62 lbs

Dogs Like George

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Discover dogs who share a similar breed mix to George. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Boston Terrier
Great Dane
Labrador Retriever
American Pit Bull Terrier

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George
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Boston Terrier mix Great Dane / Labrador Retriever mix Boston Terrier American Pit Bull Terrier / Boston Terrier mix Great Dane Labrador Retriever Boston Terrier Boston Terrier American Pit Bull Terrier Boston Terrier mix Great Dane Great Dane Labrador Retriever Labrador Retriever

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain George’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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George has one variant that you should let your vet know about.

ALT Activity

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George inherited one copy of the variant we tested

Why is this important to your vet?

George has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that George has this genotype, as ALT is often used as an indicator of liver health and George is likely to have a lower than average resting ALT activity. As such, an increase in George’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Day Blindness

Identified in Labrador Retrievers

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers and Labrador Retrievers

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Alexander Disease

Identified in Labrador Retrievers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Narcolepsy

Identified in Labrador Retrievers

Limb Girdle Muscular Dystrophy

Identified in Boston Terriers

Centronuclear Myopathy

Identified in Labrador Retrievers

Exercise-Induced Collapse

Identified in Labrador Retrievers

Inherited Myopathy of Great Danes

Identified in Great Danes

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Ichthyosis

Identified in Great Danes

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Red Pigment Intensity LINKAGE
I (Intensity) Loci
No impact on coat pattern
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
No Call
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
No impact on coat pattern
White Spotting
S (White Spotting) Locus
Likely to have little to no white in coat
Merle
M (Merle) Locus
Unlikely to have merle pattern
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through George’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A377

Map

A1a

George’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A377

George’s Haplotype

Part of the large A1a haplogroup, this rare haplotype occurs in dogs with European ancestry.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through George’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.43

Map

A1b

George’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.43

George’s Haplotype

Part of the A1b haplogroup, the Ha.43 haplotype occurs most commonly in Great Danes, Portuguese Podengo Pequenos and Rhodesian Ridgebacks. We've also spotted it in American Village Dogs.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

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