“Rosie”
Ch. Gatehouse Undeniable

Doberman Pinscher

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Registration

CKC: EG706070

Genetic Breed Result

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Doberman Pinscher

Doberman Pinscher Doberman Pinscher
Doberman Pinschers are a strong and athletic breed that are built to guard and protect.
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Genetic Stats


Predicted Adult Weight
Genetic Age
35 human years Learn More
Based on the date of birth provided
Changes to this dog’s profile
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  • On 1/22/2019 changed name from "Gatehouse Undeniable" to "Ch. Gatehouse Undeniable"

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Health Summary

Rosie is at increased risk for one genetic health condition.

Dilated Cardiomyopathy, DCM2

Rosie inherited one copy of the variant we tested

How to interpret this result

Rosie has one copy of a variant in the TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Rosie shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Rosie. We measure this result using a linkage test.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

Von Willebrand Disease Type I (VWF)

Identified in Doberman Pinschers

Dilated Cardiomyopathy, DCM1 (PDK4)

Identified in Doberman Pinschers

Additional Genetic Conditions


Clinical Tools

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (EE)
K Locus (CBD103)
More likely to have a patterned haircoat (kyky)
A Locus (ASIP)
Black/Brown and tan coat color pattern (atat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (DD)
B Locus (TYRP1)
Brown hair and skin (bb)
S Locus (MITF)
Likely flash, parti, piebald, or extreme white (spsp)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Coat Texture (KRT71)
Likely straight coat (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Larger (NN)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Rosie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B45

Map

B1

Ch. Gatehouse Undeniable’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B45

Ch. Gatehouse Undeniable’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, Doberman Pinschers, Cocker Spaniels, and village dogs in Costa Rica.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Rosie inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Rosie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.