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Freckle

Mixed Ancestry

No bio has been provided yet

Place of Birth

England, United Kingdom

Current Location

Münster, North Rhine-Westphalia, Germany

From

Manchester, UK

This dog has been viewed and been given 19 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Russell-type Terrier

These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Bull Terrier

The Bull Terrier, sometimes called the English Bull Terrier, is perhaps most famous for its egg-shaped head (and being Target's mascot). This breed can be overly rambunctious and play rough, so early training and socialization is important. However, they make lovely companions for active homes, and Bull Terrier owners delight in the breed's sense of humor.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Dogs Like Freckle

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Discover dogs who share a similar breed mix to Freckle. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Russell-type Terrier
American Pit Bull Terrier
Bull Terrier
German Shepherd Dog
Supermutt

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Here’s what Freckle’s family tree may have looked like.
Freckle
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Russell-type Terrier mix Russell-type Terrier / Bull Terrier mix German Shepherd Dog mix Russell-type Terrier American Pit Bull Terrier mix Russell-type Terrier Bull Terrier mix German Shepherd Dog mix Mixed Russell-type Terrier Russell-type Terrier American Pit Bull Terrier American Pit Bull Terrier mix
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Freckle’s breed mix.
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Health Summary

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Freckle inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Freckle inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Freckle’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Freckle is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Freckle inherited one copy of the variant we tested

Why is this important to your vet?

Freckle has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Freckle has this genotype, as ALT is often used as an indicator of liver health and Freckle is likely to have a lower than average resting ALT activity. As such, an increase in Freckle’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Platelet Factor X Receptor Deficiency, Scott Syndrome

Identified in German Shepherd Dogs

Severe Combined Immunodeficiency, SCID

Identified in Russell-type Terriers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Day Blindness

Identified in German Shepherd Dogs

Primary Lens Luxation

Identified in Bull Terriers and Russell-type Terriers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers, German Shepherd Dogs, and more

Polycystic Kidney Disease, PKD

Identified in Bull Terriers

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers and Bull Terriers

Enamel Hypoplasia

Identified in Russell-type Terriers

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Russell-type Terriers

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs and Russell-type Terriers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Congenital Myasthenic Syndrome, CMS

Identified in Russell-type Terriers

Laryngeal Paralysis

Identified in Bull Terriers

Lethal Acrodermatitis, LAD

Identified in Bull Terriers

Intervertebral Disc Disease (Type I)

Identified in Russell-type Terriers

β-Mannosidosis

Identified in Mixed-breed dogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Freckle’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B95

Map

B1

Freckle’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B95

Freckle’s Haplotype

Part of the B1 haplogroup, we see this haplotype most frequently in mixed breed dogs.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Freckle inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Freckle is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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