What is Embark?

Frankie

Mixed Breed

Chat

“Frankie was adopted from an Arizona shelter at the age of 7. He's the happiest, sweetest little soul you could ever imagine who loves walks and chasing tennis balls. At the age of 10, he suddenly went blind with PLL and Glaucoma and required enucleation of both eyes within a year. He has adapted wonderfully and continues to be highly active and a true joy.”

Instagram tag
@maxwellfrankie

Location
Montana, USA
From
Phoenix, AZ, USA

This dog has been viewed 269 times and been given 26 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

88.2% Russell-type Terrier
11.8% Smooth Fox Terrier
Russell-type Terrier Russell-type Terrier
These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.
Learn More
Smooth Fox Terrier Smooth Fox Terrier
The Smooth Fox Terrier has the distinction of being the first terrier recognized by the Kennel Club in the United Kingdom. Doesn’t sound impressive? Well, it is! The breed received this honor in 1875, which is a good deal earlier than most other breeds, terrier or not. Their notoriety stems partly from the fact that they have been a popular and distinct breed for quite some time, at least since the 18th century. They made their way to the United States not long after, and they were officially recognized by the American Kennel Club in 1885.
Learn More
Start a conversation! Message this dog’s humans.

Genetic Stats

Wolfiness: 0.9 % MEDIUM Learn More
Predicted Adult Weight: 21 lbs Learn More
Genetic Age: 78 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Frankie’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Russell-type Terrier
Smooth Fox Terrier

Explore:

Family tree

Health

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Russell-type Terrier mix Russell-type Terrier mix Russell-type Terrier Russell-type Terrier mix Russell-type Terrier Russell-type Terrier / Smooth Fox Terrier mix Russell-type Terrier Russell-type Terrier Russell-type Terrier Russell-type Terrier mix Russell-type Terrier Russell-type Terrier Russell-type Terrier Smooth Fox Terrier mix
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Frankie’s breed mix, but this family tree may not be the only possible one.

Explore:

Health

Maternal Haplotype

Paternal Haplotype

Summary

2
AT RISK
0
CARRIER
166
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Frankie has two copies of a mutation associated with reduced ALT activity. Please inform your veterinarian that Frankie has this genotype, as ALT is often used as an indi…

At Risk for 2 genetic conditions

Frankie has tested positive for 2 of the genetic diseases that Embark tests for.
What does At Risk mean?

Testing positive is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.

Please consult with your veterinarian to determine the best course of action.

Condition List

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Dilated Cardiomyopathy
(PDK4)
Heart

The most common acquired heart disease of dogs, this is a progressive disease of the heart ventricles: early diagnosis and treatment is key. The ventricles are the heavil…

Not A Carrier

Good news! Frankie is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Frankie tested clear for 6 genetic conditions that are common in his breed mix.
Condition List

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Russell-type Terriers, but not Frankie.

Severe Combined Immunodeficiency
(PRKDC)
Immune

Due to a poorly functioning immune system, affected dogs require close monitoring for signs of infection. SCID dogs cannot produce functional B-lymphocytes, the cells res…

Seen in Russell-type Terriers, but not Frankie.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Russell-type Terriers, Smooth Fox Terriers, but not Frankie.

Spinocerebellar Ataxia, Late-Onset Ataxia
(CAPN1)
Brain and Spinal Cord

Known as the “oldest” (even reptiles and more ancient species have them!) part of the brain, the cerebellum fine-tunes motor signals from the brain to the muscles, allowi…

Seen in Russell-type Terriers, but not Frankie.

Spinocerebellar Ataxia with Myokymia and/or Seizures
(KCNJ10)
Brain and Spinal Cord

Known as the “oldest” (even reptiles and more ancient species have them!) part of the brain, the cerebellum fine-tunes motor signals from the brain to the muscles, allowi…

Seen in Russell-type Terriers, Smooth Fox Terriers, but not Frankie.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Russell-type Terriers, Smooth Fox Terriers, but not Frankie.

Other Conditions: Clear of 160

Frankie is clear of 160 other genetic diseases that Embark tests for.

Explore:

Family tree

Maternal Haplotype

Paternal Haplotype

Through Frankie’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B6/8/67

Map

B1

Frankie’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B6/8/67

Frankie’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in village dogs from South America to the Middle East, all the way down to the French Polynesian Islands. Among the 12 breed dogs we have seen it in, it occurs most frequently among German Shepherd Dogs, English Springer Spaniels, and Havanese.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Explore:

Family tree

Health

Paternal Haplotype

Through Frankie’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7

Map

D

Frankie’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7

Frankie’s Haplotype

Part of the D haplogroup, this common haplotype has been found in French Bulldogs, Afghan Hounds, Bull Terriers, and village dogs spanning from South America to Africa and into the South Pacific.

Some other Embark dogs with this haplotype:

The D paternal lineage is common in Boxers.

Explore:

Family tree

Health

Maternal Haplotype