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Frankie

Mixed Breed

“Frankie was adopted from an Arizona shelter at the age of 7. He's the happiest, sweetest little soul you could ever imagine who loves walks and chasing tennis balls. At the age of 10, he suddenly went blind with PLL and Glaucoma and required enucleation of both eyes within a year. He has adapted wonderfully and continues to be highly active and a true joy.”

Instagram tag
@maxwellfrankie

Current Location
Phoenix, Arizona, USA
From
Phoenix, AZ, USA

This dog has been viewed 1542 times and been given 53 wags

Genetic Breed Result

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Mixed Breed

88.2% Russell-type Terrier
11.8% Smooth Fox Terrier
Russell-type Terrier Russell-type Terrier
These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.
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Smooth Fox Terrier Smooth Fox Terrier
The Smooth Fox Terrier has the distinction of being the first terrier recognized by the Kennel Club in the United Kingdom. Doesn’t sound impressive? Well, it is! The breed received this honor in 1875, which is a good deal earlier than most other breeds, terrier or not. Their notoriety stems partly from the fact that they have been a popular and distinct breed for quite some time, at least since the 18th century. They made their way to the United States not long after, and they were officially recognized by the American Kennel Club in 1885.
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Genetic Stats


Wolfiness

0.9 % MEDIUM Learn More

Predicted Adult Weight
Genetic Age
87 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Frankie’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Russell-type Terrier
Smooth Fox Terrier

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Russell-type Terrier mix Russell-type Terrier mix Russell-type Terrier Russell-type Terrier mix Russell-type Terrier Russell-type Terrier / Smooth Fox Terrier mix Russell-type Terrier Russell-type Terrier Russell-type Terrier Russell-type Terrier mix Russell-type Terrier Russell-type Terrier Russell-type Terrier Smooth Fox Terrier mix

Our algorithms predict this is the most likely family tree to explain Frankie’s breed mix, but this family tree may not be the only possible one.

Health Summary

Frankie inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy - crd4/cord1

Frankie inherited both copies of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Frankie will develop this disease.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with the breeds in Frankie have been studied to know whether or not this variant will increase Frankie’s risk of developing this disease.

What is Progressive Retinal Atrophy - crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.


Dilated Cardiomyopathy, DCM1

Frankie inherited both copies of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Frankie will develop this disease.

Scientific Basis

Dogs with similar breeds to Frankie are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Frankie.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.


ALT Activity

Frankie inherited both copies of the variant we tested

Why is this important to your vet?

Frankie has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Frankie's ALT activity above their current, healthy, ALT activity. As an increase above Frankie’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Congenital Macrothrombocytopenia

Identified in Russell-type Terriers

Severe Combined Immunodeficiency

Identified in Russell-type Terriers

Primary Lens Luxation

Identified in Russell-type Terriers and Smooth Fox Terriers

Urate Kidney & Bladder Stones

Identified in Russell-type Terriers

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Russell-type Terriers and Smooth Fox Terriers

Intervertebral Disc Disease (Type I)

Identified in Russell-type Terriers

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Black/Brown and tan coat color pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
Likely saddle tan patterned
Merle
M (Merle) Locus
Unlikely to have merle pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation

Through Frankie’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B6/8/67

Map

B1

Frankie’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B6/8/67

Frankie’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in village dogs from South America to the Middle East, all the way down to the French Polynesian Islands. Among the 12 breed dogs we have seen it in, it occurs most frequently among German Shepherd Dogs, English Springer Spaniels, and Havanese.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Through Frankie’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7

Map

D

Frankie’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7

Frankie’s Haplotype

Part of the D haplogroup, this common haplotype has been found in French Bulldogs, Afghan Hounds, Bull Terriers, and village dogs spanning from South America to Africa and into the South Pacific.

Some other Embark dogs with this haplotype:

The D paternal lineage is common in Boxers.