Stara inherited one copy of the variant we tested
No Dogs Available
It looks like you don’t have any dogs on your account yet. Activate a kit now!
“Stara have very nice character. She loves all Peoples.”
This dog has been viewed
Start a conversation! Message this dog’s owner.
Explore
Health Summary
Stara inherited one variant that you should learn more about.
And one variant that you should tell your vet about.
Degenerative Myelopathy, DM
What does this result mean?
This variant should not impact Stara’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Stara is unlikely to develop this condition due to this variant because she only has one copy of the variant.
Impact on Breeding
Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.
What is Degenerative Myelopathy, DM?
The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
ALT Activity
Stara inherited one copy of the variant we tested
Why is this important to your vet?
Stara has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Stara has this genotype, as ALT is often used as an indicator of liver health and Stara is likely to have a lower than average resting ALT activity. As such, an increase in Stara’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
Multiple Drug Sensitivity (ABCB1)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Hemophilia A (F8 Exon 11, German Shepherd Variant 1)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Hemophilia A (F8 Exon 1, German Shepherd Variant 2)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Day Blindness (CNGA3 Exon 7, German Shepherd Variant)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Urate Kidney & Bladder Stones (SLC2A9)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
X-Linked Hereditary Nephropathy, XLHN (COL4A5 Exon 35, Samoyed Variant 2)
Identified in Samoyeds
Variant not detected
Anhidrotic Ectodermal Dysplasia (EDA Intron 8)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)
Identified in Czechoslovakian Vlcaks and German Shepherd Dogs
Variant not detected
GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)
Identified in Siberian Huskies
Variant not detected
Additional Genetic Conditions
Explore
What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.