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Fern

Sheepadoodle

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Genetic Breed Result

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Old English Sheepdog

The Old English Sheepdog is a spirited breed that likes to show of its working ability and that amazing shaggy coat. These guys have been around since the early 1800's and are still best used as herding dogs. They can make great family pets as long as you are ready to fill their exercise and grooming needs.

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Poodle (Small)

A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.

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DNA Breed Origins

Breed colors:
Old English Sheepdog
Poodle (Small)

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Health Summary

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Fern has one variant that you should let your vet know about.

ALT Activity

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Fern inherited one copy of the variant we tested

Why is this important to your vet?

Fern has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Fern has this genotype, as ALT is often used as an indicator of liver health and Fern is likely to have a lower than average resting ALT activity. As such, an increase in Fern’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Old English Sheepdogs

Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Small Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Small Poodles

Primary Ciliary Dyskinesia, PCD (CCDC39 Exon 3, Old English Sheepdog Variant)

Identified in Old English Sheepdogs

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Small Poodles

Hereditary Ataxia, Cerebellar Degeneration (RAB24, Old English Sheepdog and Gordon Setter Variant)

Identified in Old English Sheepdogs

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Small Poodles

Exercise-Induced Collapse, EIC (DNM1)

Identified in Old English Sheepdogs

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Small Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Small Poodles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Fern’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247/A522

Map

A1d

Fern’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247/A522

Fern’s Haplotype

Part of the A1d haplogroup, the A247/A522 haplotype occurs most frequently in Pomeranians, Dachshunds, and Australian Shepherds.

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Fern inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Fern is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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