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“Falkor”
UKC GRAND CHAMPION Talisman Ardent Falkors Luck

Silken Windhound

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Registration

ISWS: 2012-356/01

Genetic Breed Result

Talisman Ardent Falkors Luck

“Falkor”
UKC GRAND CHAMPION Talisman Ardent Falkors Luck

Silken Windhound
100.0% Silken Windhound

Silken Windhound

These gentle dogs are descended from the larger Borzoi, the shorter-coated Whippet, and a bit of Sheltie, but are today very much a breed all their own.

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Genetic Stats

Predicted Adult Weight

50 lbs

Genetic Age
72 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 11/3/2017 changed name from "Falkor" to "Talisman Ardent Falkors Luck"

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Our algorithms predict this is the most likely family tree to explain Falkor’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Falkor is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Multiple Drug Sensitivity

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Falkor inherited one copy of the variant we tested

How to interpret this result

Falkor has one copy of a variant at the ABCB1 gene and is at risk for displaying adverse drug reactions. While he may not be as severely affected as a dog with two copies of the ABCB1 drug sensitivity allele, normal dosages of drugs could still have potentially severe effects on Falkor. Please inform your veterinarian that Falkor carries this variant; it is essential that they know this information before prescribing drugs.

What is Multiple Drug Sensitivity?

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with a mutation in the ABCB1 gene.

ALT Activity

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Falkor inherited one copy of the variant we tested

Why is this important to your vet?

Falkor has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Falkor has this genotype, as ALT is often used as an indicator of liver health and Falkor is likely to have a lower than average resting ALT activity. As such, an increase in Falkor’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Collie Eye Anomaly (NHEJ1)

Identified in Silken Windhounds

Additional Genetic Conditions

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Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (Ee)
K Locus (CBD103)
More likely to have a mostly solid black or brown coat (KBky)
Intensity Loci LINKAGE
No impact on coat pattern (Dilute Red Pigmentation)
A Locus (ASIP)
Not expressed (ayat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (Dd)
B Locus (TYRP1)
Black or gray hair and skin (BB)
S Locus (MITF)
Likely flash, parti, piebald, or extreme white (spsp)
H Locus (Harlequin)
hh
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely long coat (TT)
Shedding (MC5R)
Likely heavy/seasonal shedding (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Likely to have hind dew claws (CT)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Larger (NN)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)
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Through Falkor’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1b

Map

B1

Talisman Ardent Falkors Luck’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1b

Talisman Ardent Falkors Luck’s Haplotype

Part of the large B1 haplogroup, we see this haplotype in village dogs across the world, including those from Central America, the Middle East, South Asia, and the French Polynesian Islands. Among the 31 breed dogs we see it in, we see it in Poodles, Otterhounds, and Labrador Retrievers. It is also our most commonly-sampled Golden Retriever haplotype!

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Falkor’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.10

Map

A1a

Talisman Ardent Falkors Luck’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.10

Talisman Ardent Falkors Luck’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in village dogs throughout Africa and down into the South Pacific. Among breeds, this haplotype occurs in 5 breeds and is most common among Shetland Sheepdogs, Border Collies, and Cairn Terriers.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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