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Eva

Yorkshire Terrier

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“Eva's very athletic. Loves hiking, swimming, and kayaking. She is very sweet and very clever. I adopted Eva in Jan 2016 from Mostly Shepherds Rescue in New Jersey.”

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@stressedandfabulous

Current Location

Connecticut, USA

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Genetic Breed Result

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Yorkshire Terrier

Petite but proud, the Yorkshire terrier is a popular toy breed with a silky, low-shedding coat.

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Eva’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Eva inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Dilated Cardiomyopathy, DCM1

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Eva inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Eva will develop this disease.

Scientific Basis

Dogs with similar breeds to Eva are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Eva.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Eva inherited one copy of the variant we tested

Why is this important to your vet?

Eva has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Eva has this genotype, as ALT is often used as an indicator of liver health and Eva is likely to have a lower than average resting ALT activity. As such, an increase in Eva’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd

Identified in Yorkshire Terriers

Primary Lens Luxation

Identified in Yorkshire Terriers

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Eva’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C35

Map

C1

Eva’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C35

Eva’s Haplotype

Part of the C1 haplogroup, the C35 haplotype occurs most commonly in Yorkshire Terriers. It's a rare find!

Some other Embark dogs with this haplotype:

The C1 maternal line is commonly found in Jackals.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Eva inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Eva is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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