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Ethel

Mixed Ancestry

“She loves to tell us when it's time to eat. When she was younger, she learned lots of cool tricks like jump and dance.”

Current Location

Columbus, Ohio, USA

From

Columbus, Ohio, USA

This dog has been viewed and been given 2 wags

Registration

Microchip: 4B7E413658

Genetic Breed Result

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Pug

The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. Pugs are known for being sociable and gentle companion dogs.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Dogs Like Ethel

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Discover dogs who share a similar breed mix to Ethel. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Pug
Pomeranian

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Here’s what Ethel’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Ethel’s breed mix.

Breed Reveal Video

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Health Summary

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Ethel inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Ethel inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Ethel’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Ethel is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Ethel inherited both copies of the variant we tested

Why is this important to your vet?

Ethel has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Ethel's ALT activity above their current, healthy, ALT activity. As an increase above Ethel’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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May-Hegglin Anomaly

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Pugs

Methemoglobinemia

Identified in Pomeranians

Progressive Retinal Atrophy, rcd3

Identified in Pomeranians

Urate Kidney & Bladder Stones

Identified in Pomeranians

Oculocutaneous Albinism, OCA

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets

Identified in Pomeranians

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Ethel’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A240

Map

A1b

Ethel’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A240

Ethel’s Haplotype

Part of the large A1b haplogroup, this haplotype has been spotted in village dogs in Portugal, Costa Rica, and Brazil. Among the breeds we have seen it in, it occurs most often in Miniature Schnauzers, Pugs, and Maltese. Not confined to small breeds, we also see this haplotype in Pharaoh Hounds and Ibizan Hounds.

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Ethel inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ethel is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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