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Enzo CGC CGCA

Mixed Breed

“I found Enzo in a shelter when he was 4 months old and only 15 lbs. He looked like a malinois and was super shy around people. It didn't take him long to come out of his shell and be my best friend. now he is my little velcro dog who loves to work and play. He currently weighs 45 lbs at 19 months”

Place of birth
Phoenix, Arizona, USA
Location
Mesa, Arizona, USA
From
Tempe, AZ, USA

This dog has been viewed 989 times and been given 8 wags

Genetic Breed Result

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Mixed Breed

42.1% German Shepherd Dog
16.2% American Pit Bull Terrier
12.2% American Staffordshire Terrier
11.4% Chow Chow
10.2% American Bulldog
7.9% Samoyed
German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence.
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American Pit Bull Terrier American Pit Bull Terrier
Few dogs are more recognizable than the American Pit Bull Terrier. While they originated in the British Isles and are descendants of the Mastiff-type dogs introduced to England in antiquity, the American Pit Bull Terrier was brought over to the United States by English immigrants in the 1800s. They quickly became one of the most popular and widespread breeds there.
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American Staffordshire Terrier American Staffordshire Terrier
American Staffordshire Terrier's are powerul but playful dogs, that are both loyal and affectionate with their owners.
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Chow Chow Chow Chow
This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. He can be aloof — if you’re looking for a cuddle buddy, this probably isn’t the best breed for you — and downright suspicious of strangers. But for the right person, he’s a fiercely loyal companion.
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American Bulldog American Bulldog
American bulldogs are enjoying a healthy increase in popularity, either as a working/protector dog or as a family pet. All over the world, they are used variously as "hog dogs" (catching escaped pigs or hunting razorbacks), as cattle drovers and as working or sport K-9s. American Bulldogs also successfully compete in several dog sports such as dog obedience, Iron Dog competition and weight pulling.
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Samoyed Samoyed
A working breed, the Samoyed can be strong-willed at times, but above all they remain friendly, gentle, and devoted family dogs. The Samoyed was originally bred to hunt, haul sledges, and herd reindeer. Among the breed’s duties: pack hiking, tracking, and warming their owners by sleeping on top of them at night.
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Genetic Stats

Wolfiness: 1.1 % MEDIUM Learn More
Predicted Adult Weight: 73 lbs Learn More
Genetic Age: 22 human years Learn More

Explore other Embark dogs who have breed mixes that are similar to Enzo’s.
A Mix Match of 100 means they are the exact same breed mix!

Breed Mix Matches

DNA Breed Origins

What’s this?
Breed colors:
German Shepherd Dog
American Pit Bull Terrier
American Staffordshire Terrier
Chow Chow
American Bulldog
Samoyed

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed German Shepherd Dog mix American Pit Bull Terrier / American Bulldog mix American Staffordshire Terrier / Chow Chow mix German Shepherd Dog German Shepherd Dog / Samoyed mix American Pit Bull Terrier American Bulldog American Staffordshire Terrier Chow Chow German Shepherd Dog German Shepherd Dog German Shepherd Dog Samoyed mix
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Enzo’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
0
CARRIER
165
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Enzo has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Enzo has this …

Not At Risk

Good news! Enzo did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Enzo does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Enzo’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Enzo is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Enzo tested clear for 18 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Enzo.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in German Shepherd Dogs, but not Enzo.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in German Shepherd Dogs, but not Enzo.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Enzo.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A largely benign disease of red blood cell shape, elliptocytosis rarely causes symptoms. Upon examinatino of a blood smear, however, affected dogs have elongated, oval or…

Seen in Chow Chows, but not Enzo.

Progressive Retinal Atrophy - crd1
(PDE6B)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Enzo.

Progressive Retinal Atrophy - crd2
(IQCB1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Enzo.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Enzo.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a nonprogressive retinal disease that, in rare cases, can lead to vision loss. All known mutations lie in the BEST1 gene and are inherited in an autosomal recessi…

Seen in American Bulldogs, but not Enzo.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, American Bulldogs, but not Enzo.

X-Linked Hereditary Nephropathy (Samoyed Variant 2)
(COL4A5 Exon 35)
Kidney and Bladder

This condition causes inappropriate loss of protein in the urine, which leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and excessive thirst a…

Seen in Samoyeds, but not Enzo.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Enzo.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Enzo.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Enzo.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia - NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Enzo.

Neuronal Ceroid Lipofuscinosis 10
(CTSD Exon 5)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Bulldogs, but not Enzo.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in German Shepherd Dogs, American Pit Bull Terriers, American Staffordshire Terriers, Chow Chows, American Bulldogs, Samoyeds, but not Enzo.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in German Shepherd Dogs, American Pit Bull Terriers, American Staffordshire Terriers, Chow Chows, American Bulldogs, Samoyeds, but not Enzo.

Other Conditions: Clear of 147

Enzo is clear of 147 other genetic diseases that Embark tests for.

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Family tree

Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
EmEm
K Locus (Dominant Black)
kyky
A Locus (Agouti, Sable)
ayat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
Bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CT
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NI
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Enzo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Enzo’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Enzo’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Family tree

Health

Traits

Paternal Haplotype

Through Enzo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C

Haplotype

H5a

Map

C

Enzo’s Haplogroup

C is a relatively rare paternal lineage. The dog populations which bear C are a disparate bunch. The Akita and Shiba Inu are Japanese breeds, the former of which seems to have roots in the Jomon population of hunter-gatherers which were present in the islands of Japan before the ancestors of the modern Japanese arrived. The New Guinea Singing Dog, Samoyed, and Alaska Malamute are all disparate breeds that also represent the C lineage. One village dog from Peru also bore this lineage. This wide distribution and diversity suggest C is not a recently expanded lineage. It likely represents a canid lineage which diversified sometime around the Last Glacial Maximum, when the dogs of Siberia and Oceania split off and went their separate ways.

H5a

Enzo’s Haplotype

Part of the C haplogroup, this haplotype occurs most commonly in Akitas and Alaskan Malamutes.

Some other Embark dogs with this haplotype:

The Shiba Inu descends from this relativey rare haplogroup.

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Family tree

Health

Traits

Maternal Haplotype