Frog inherited one copy of the variant we tested
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Changes to this dog’s profile
- On 1/7/2023 changed name from "Ella’s male puppy" to "B-Joli Free Rocket over Ground"
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Health Summary
Frog inherited two variants that you should learn more about.
Congenital Macrothrombocytopenia
What does this result mean?
This variant should not impact Frog’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Frog is unlikely to develop this condition due to this variant because he only has one copy of the variant.
Impact on Breeding
Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.
What is Congenital Macrothrombocytopenia?
This is a benign disorder of platelet production that leads to abnormally large, sparse platelets.
Degenerative Myelopathy, DM
Frog inherited both copies of the variant we tested
What does this result mean?
We do not know whether this increases the risk that Frog will develop Degenerative Myelopathy, DM.
Scientific Basis
Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Frog's breed have been studied to know whether or not this variant will increase Frog's risk of developing this disease.
Impact on Breeding
Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Degenerative Myelopathy, DM in your breeding program and related dogs.
What is Degenerative Myelopathy, DM?
The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
Breed-Relevant Genetic Conditions
Primary Lens Luxation (ADAMTS17)
Identified in Norfolk Terriers
Variant not detected
Ichthyosis, Epidermolytic Hyperkeratosis (KRT10, Terrier Variant)
Identified in Norfolk Terriers
Variant not detected
Additional Genetic Conditions
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What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.