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“Miles”
GCH Electron n’ Foxfire’s V.I.P. Access RA DCAT CGC TKN WAC

Doberman Pinscher

“Miles was owner handled to his AKC CH title, finishing at the Enumclaw WA shows including a BOW/BOH/Award of merit at the Puget Sound DPC specialty. He finished his GCH title in October 2019. Miles was a 2019 DPCA Top 20 OHS finalist. Miles earned his WAC and RA titles ti become a 4th generation ROM in 2022. He won a BISS, 2 BOSS and several Select Dog awards in 2022 after taking several years off from the conformation ring.”

Current Location

Stevensville, Montana, USA

This dog has been viewed and been given 3 wags

Registration

American Kennel Club (AKC): WS58062703

Genetic Breed Result

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Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

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Health Summary

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Miles is at increased risk for two genetic health conditions.

Von Willebrand Disease Type I, Type I vWD

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Miles inherited one copy of the variant we tested

How to interpret this result

Miles has one copy of this variant in the VWF gene and will likely have decreased levels of vWF compared to a dog without this variant. However, they will have higher levels of vWF than a dog with two copies of this variant. There is a slightly increased risk of bleeding in dogs with one copy of the variant, particularly when other clotting issues are also present. Please consult your veterinarian for further diagnostic and care options.

What is Von Willebrand Disease Type I, Type I vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.

Dilated Cardiomyopathy, DCM2

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Miles inherited one copy of the variant we tested

How to interpret this result

Miles has one copy of a variant in the TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks Miles shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for Miles.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

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Dilated Cardiomyopathy, DCM1 (PDK4, Doberman Pinscher Variant 1)

Identified in Doberman Pinschers

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

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Other Body Features

Body Size

Body Size

Performance

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Through Miles’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C25

Map

C1

Electron n’ Foxfire’s V.I.P. Access’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C25

Electron n’ Foxfire’s V.I.P. Access’s Haplotype

Part of the C1 haplogroup, this haplotype has been spotted in village dogs in Peru and Namibia. Among breeds, it occurs most frequently in Doberman Pinschers, but has also been detected in German Shepherd Dogs and Labrador Retrievers.

The C1 maternal line is commonly found in Jackals.

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Through Miles’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.3

Map

A1b

Electron n’ Foxfire’s V.I.P. Access’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.3

Electron n’ Foxfire’s V.I.P. Access’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs in Peru and the French Polynesian Islands. It is also common among Doberman Pinscher, Saint Bernard, and Rhodesian Ridgeback.

Great Danes and Pomeranians have this in common!

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