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Ebon CGC

Labrador Retriever

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  • September 2017

“Ebon was the puppy nobody wanted. He was bred to be a working retriever but no hunter who met him wanted him. So, he was given to a pet home free of charge. He's a bit of a mess: full of anxiety and in his younger days he had so much drive that if he was allowed to he would fetch until he overheated. He has an absurdly soft temperament and doesn't respond well to harshness, which causes him to shut down. He has rust markings on his legs (like his mom) and had a brother born with a red mustache.”

This dog has been viewed 165 times and been given 5 wags

Genetic Breed Result

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Labrador Retriever

100.0% Labrador Retriever
Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
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Genetic Stats

Wolfiness: 2.5 % HIGH Learn More
Predicted Adult Weight: 57 lbs Learn More
Genetic Age: 100 human years Learn More

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

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Our algorithms predict this is the most likely family tree to explain Ebon’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
1
CARRIER
165
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Ebon has two normal alleles at ALT.

Not At Risk

Good news! Ebon did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Ebon does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Ebon’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Carrier for 1 genetic condition

Ebon is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?

Ebon has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Ebon ever has children.

Condition List

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Common Conditions

Good news! Ebon tested clear for 17 genetic conditions that are common in his breed.
Condition List

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Macular Corneal Dystrophy (MCD)
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as 1 month, the sy…

Myotubular Myopathy 1, X-linked Myotubular Myopathy
(MTM1)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Congenital Myasthenic Syndrome
(COLQ)
Neuro-muscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Skeletal Dysplasia 2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Other Conditions: Clear of 148

Ebon is clear of 148 other genetic diseases that Embark tests for.

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Family tree

Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Eme
K Locus (Dominant Black)
KBKB
A Locus (Agouti, Sable)
atat
D Locus (Dilute, Blue, Fawn)
No Call
B Locus (Brown, Chocolate, Liver, Red)
Bb

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
II
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GA
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Ebon’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Ebon’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Ebon’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Family tree

Health

Traits

Paternal Haplotype

Through Ebon’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.8

Map

A1a

Ebon’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.8

Ebon’s Haplotype

Part of the large A1a haplogroup, this very common haplotype occurs in village dogs throughout the world (including southeast Asia, which is uncommon for A1a’s). Among the 25 breeds we see this haplotype in, it occurs most frequently in Labrador Retriever, Vizsla, and English Springer Spaniel.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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Family tree

Health

Traits

Maternal Haplotype