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Duncan

Mixed Ancestry

“We found him on the side of the road only a few weeks old. He sure is a character, he loves to talk to you, and is the world's best snuggler - if he's in the mood for it. I bet he could set the record for most tennis balls fetched in one go.”

Current Location

Williamsburg, Virginia, USA

From

Suffolk, Virginia, USA

This dog has been viewed and been given 0 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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American Eskimo Dog

American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Miniature Pinscher

The Miniature Pinscher is a small breed of dog originating from Germany. The breed's earliest ancestors may have included the German Pinscher mixed with Italian greyhounds and dachshunds.

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Collie

Collies are attractive herding dogs, boasting a beautiful coat while being highly intelligent. They also make for extremely loyal and sweet family pets.

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Dogs Like Duncan

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Discover dogs who share a similar breed mix to Duncan. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Beagle
American Eskimo Dog
Cocker Spaniel
Golden Retriever
Boxer
Miniature Pinscher
Collie
Supermutt

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Here’s what Duncan’s family tree may have looked like.
Duncan
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Beagle mix Mixed Beagle American Eskimo Dog mix Cocker Spaniel / Golden Retriever mix Boxer / Miniature Pinscher mix Beagle Beagle American Eskimo Dog Mixed Cocker Spaniel mix Golden Retriever mix Boxer mix Miniature Pinscher mix
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Duncan’s breed mix.
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Health Summary

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Duncan is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Duncan inherited one copy of the variant we tested

How to interpret this result

Duncan has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Duncan inherited one copy of the variant we tested

Why is this important to your vet?

Duncan has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Duncan has this genotype, as ALT is often used as an indicator of liver health and Duncan is likely to have a lower than average resting ALT activity. As such, an increase in Duncan’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Collies

Factor VII Deficiency

Identified in Beagles

Hemophilia A

Identified in Boxers

Thrombopathia

Identified in American Eskimo Dogs

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, prcd

Identified in American Eskimo Dogs, Cocker Spaniels, and more

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Collie Eye Anomaly

Identified in Collies

Primary Open Angle Glaucoma

Identified in Beagles

Primary Lens Luxation

Identified in American Eskimo Dogs

Cystinuria Type II-B

Identified in Miniature Pinschers

Familial Nephropathy

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in American Eskimo Dogs, Boxers, and more

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Muscular Dystrophy

Identified in Golden Retrievers

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Osteogenesis Imperfecta

Identified in Golden Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Duncan’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18/19/20/21/27/36/94/109

Map

A1b

Duncan’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18/19/20/21/27/36/94/109

Duncan’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in over 25 countries across the world. We have detected this haplotype in lots of breeds, and it occurs most commonly in German Shepherd Dogs, Maltese, English Springer Spaniels, and English Setters.

A1b is the most common haplogroup found in German Shepherds.

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Through Duncan’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.9

Map

A2b

Duncan’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.9

Duncan’s Haplotype

Part of the A2b haplogroup, this haplotype is found in village dogs spanning South America, Africa, and the South Pacific. Among the breeds we have spotted it in, the most frequent occurrences are in Dachshund, Bloodhound, American Eskimo Dog, and Jack Russell Terrier.

A2b is found in the Daschund breed.

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