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“Doc”
CH GCH VinEwood's I'm Your Huckleberry BN CD PCD OA OAJ OF SIN SEN RATO ACT1 DJ CGC TKN

English Springer Spaniel

“Doc loves life and doing all the things!”

Place of Birth

Inver Grove Heights, Minnesota, USA

Current Location

Altoona, Iowa, USA

From

Zimmerman, MN, USA

This dog has been viewed and been given 42 wags

Registration

American Kennel Club (AKC): SS12212602
Microchip: avid-601874890

Genetic Breed Result

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English Springer Spaniel

English Springer Spaniels are an energetic and loyal companion dog, bred for hunting but also popular among families.

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Changes to this dog’s profile
  • On 8/10/2023 changed name from "VinEwood's I'm Your Huckleberry "Doc"" to "VinEwood's I'm Your Huckleberry"
  • On 5/22/2020 changed name from "Doc" to "VinEwood's I'm Your Huckleberry "Doc""

Health Summary

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Doc inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Doc inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Doc’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Doc is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Doc inherited both copies of the variant we tested

Why is this important to your vet?

Doc has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Doc's ALT activity above their current, healthy, ALT activity. As an increase above Doc’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Canine Fucosidosis (FUCA1)

Identified in English Springer Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant)

Identified in English Springer Spaniels

Degenerative Myelopathy, DM (SOD1A)

Identified in English Springer Spaniels

Shaking Puppy Syndrome (PLP1, English Springer Spaniel Variant)

Identified in English Springer Spaniels

Acral Mutilation Syndrome (GDNF-AS, Spaniel and Pointer Variant)

Identified in English Springer Spaniels

Long QT Syndrome (KCNQ1)

Identified in English Springer Spaniels

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in English Springer Spaniels

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

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Other Body Features

Body Size

Body Size

Performance

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Through Doc’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A2a

Map

A1e

VinEwood's I'm Your Huckleberry’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A2a

VinEwood's I'm Your Huckleberry’s Haplotype

Part of the large A1e haplogroup, we see this haplotype in village dogs up and down the Americas as well as French Polynesia. Among the breed dogs we have detected it in, we see it most frequently in English Springer Spaniels, Papillons, and Collies.

Irish Wolfhounds are a consistent carrier of A1e.

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Through Doc’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.59

Map

A1a

VinEwood's I'm Your Huckleberry’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.59

VinEwood's I'm Your Huckleberry’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in European village dogs.

Dogs with A1a lineage travelled during European Colonial times.

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