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“Kopper”
Dent’s Doodles Big Red Boy

Goldendoodle

“Red and white Goldendoodle”

Place of Birth

Clarksville, TN, USA

Current Location

Clarksville, Tennessee, USA

From

Clarksville, TN, USA

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Registration

Canadian Kennel Club (CKC):

Genetic Breed Result

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Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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DNA Breed Origins

Breed colors:
Poodle (Standard)
Golden Retriever

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Health Summary

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Kopper inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, prcd

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Kopper inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Kopper’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Kopper is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

ALT Activity

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Kopper inherited one copy of the variant we tested

Why is this important to your vet?

Kopper has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Kopper has this genotype, as ALT is often used as an indicator of liver health and Kopper is likely to have a lower than average resting ALT activity. As such, an increase in Kopper’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1 (SLC4A3)

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)

Identified in Golden Retrievers

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 Deletion, Golden Retriever Variant)

Identified in Golden Retrievers

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Golden Retrievers and Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Muscular Dystrophy (DMD, Golden Retriever Variant)

Identified in Golden Retrievers

Congenital Myasthenic Syndrome, CMS (COLQ, Golden Retriever Variant)

Identified in Golden Retrievers

Dystrophic Epidermolysis Bullosa (COL7A1, Golden Retriever Variant)

Identified in Golden Retrievers

Ichthyosis, ICH1 (PNPLA1, Golden Retriever Variant)

Identified in Golden Retrievers

Osteogenesis Imperfecta (COL1A1, Golden Retriever Variant)

Identified in Golden Retrievers

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Kopper’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

D9

Map

D

Dent’s Doodles Big Red Boy’s Haplogroup

D is a rare maternal line, which may be the result of an ancient dog breeding with another canid, possibly a wolf. It is found in Afghan Hounds and Scandinavian dog breeds.

D9

Dent’s Doodles Big Red Boy’s Haplotype

This haplotype has been spotted in wolves and dogs with wolf ancestry. Not only is that pretty neat, but it also helps move science forward.

Afghan Hounds are one of few breeds that descends from this rare maternal line.

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Through Kopper’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.7

Map

A1b

Dent’s Doodles Big Red Boy’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.7

Dent’s Doodles Big Red Boy’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs from Lebanon and Indonesia. Among breeds, it is also found in Miniature Schnauzer and Toy Poodle.

Great Danes and Pomeranians have this in common!

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