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“Eclipse”
DeMille's Lunar Eclipse

Mixed Ancestry

No bio has been provided yet

This dog has been viewed and been given 3 wags

Genetic Breed Result

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Great Dane

Great Danes are large lovable dogs that need exercise and space. Many Great Danes are "leaners"-- they lean against their people to be closer to them, seemingly oblivious to their size!

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Weimaraner

The Weimaraner is an all-purpose gun dog. The name comes from the Grand Duke of Saxe-Weimar-Eisenach, Karl August, whose court, based in the city of Weimar (now in the state of Thuringia in modern-day Germany), enjoyed hunting.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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DNA Breed Origins

Breed colors:
Great Dane
Weimaraner
Labrador Retriever

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Here’s what Eclipse’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Eclipse’s breed mix.

Breed Reveal Video

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Health Summary

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Eclipse has one variant that you should let your vet know about.

ALT Activity

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Eclipse inherited one copy of the variant we tested

Why is this important to your vet?

Eclipse has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Eclipse has this genotype, as ALT is often used as an indicator of liver health and Eclipse is likely to have a lower than average resting ALT activity. As such, an increase in Eclipse’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Canine Elliptocytosis (SPTB Exon 30)

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency (PKLR Exon 7, Labrador Retriever Variant)

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1 (RPGRIP1)

Identified in Labrador Retrievers

Day Blindness (CNGA3 Exon 7, Labrador Retriever Variant)

Identified in Labrador Retrievers

Macular Corneal Dystrophy, MCD (CHST6)

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Labrador Retrievers and Weimaraners

Alexander Disease (GFAP)

Identified in Labrador Retrievers

Degenerative Myelopathy, DM (SOD1A)

Identified in Labrador Retrievers

Hypomyelination and Tremors (FNIP2, Weimaraner Variant)

Identified in Weimaraners

Narcolepsy (HCRTR2 Intron 6, Labrador Retriever Variant)

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM (PTPLA)

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC (DNM1)

Identified in Labrador Retrievers

Inherited Myopathy of Great Danes (BIN1)

Identified in Great Danes

X-Linked Myotubular Myopathy (MTM1, Labrador Retriever Variant)

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS (COLQ, Labrador Retriever Variant)

Identified in Labrador Retrievers

Ichthyosis (SLC27A4, Great Dane Variant)

Identified in Great Danes

Hereditary Nasal Parakeratosis, HNPK (SUV39H2)

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2 (COL11A2, Labrador Retriever Variant)

Identified in Labrador Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Eclipse’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B81

Map

B1

DeMille's Lunar Eclipse’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B81

DeMille's Lunar Eclipse’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most frequently in Shih Tzus, Chihuahuas, and Poodles.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Eclipse inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Eclipse is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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