Darwin inherited one copy of the variant we tested
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Genetic Age
Please note that genetic age is different from calendar age. We can now estimate your dog's calendar age with the Embark Age Test.
The genetic age in this report is an estimation of where your dog is in his or her healthspan. Dogs age at very different rates due to a number of genetic and environmental factors. Body size is a strong genetic influence: for example, a seven year old Great Dane is at the start of his golden years, but a seven year old Pomeranian is just learning what "slow down" means. Just within this example, you can see that the old "one doggie year = seven human years" adage isn’t going to work. And yet, knowing your dog’s age is important: it informs what your dog needs as far as food, frequency of veterinary checkups, and exercise. So how do you best determine how old your dog is?
Embark's genetic age feature calculates how old your dog would be if he or she were aging at an average human rate (using humans in the USA as the baseline). So going back to our Dane/Pom example, we'd estimate a seven year old Great Dane at about 80 years old (senior citizen), but a seven year old Pom would be about 42 (adult). Makes way more sense, right?
Calendar age | Genetic age |
---|---|
1 year | 18 human years |
2 years | 25 human years |
3 years | 30 human years |
4 years | 35 human years |
5 years | 40 human years |
6 years | 45 human years |
7 years | 50 human years |
8 years | 55 human years |
9 years | 61 human years |
10 years | 66 human years |
11 years | 71 human years |
12 years | 76 human years |
13 years | 81 human years |
14 years | 86 human years |
15 years | 92 human years |
16 years | 97 human years |
17 years | 102 human years |
18 years | 107 human years |
19 years | 112 human years |
20 years | 117 human years |
21 years | 120 human years |
All we need from you is a calendar age. It's okay if this is an estimation: it is just a starting point. We then factor in your dog's breed composition, information at certain genes that affect size, and their inbreeding coefficient to calculate genetic age. Like in humans, in dogs females tend to live longer than males (so an “80 year old” female dog = 80 year old woman). Exercise and diet also play a role in how long your dog will live. Nevertheless, genetic age is the primary risk factor for numerous diseases in dogs, including cancer, kidney disease, osteoarthritis, cataracts, cardiac disease and cognitive decline. It can help you and your vet know what you should feed your dog, what screenings to get, and other aspects of your dog’s care.
Wolfiness score
How wolfy is my dog?
Most dogs have wolfiness scores of 1% or less. We find populations and breeds with higher scores of 2-4% occasionally, and unique dogs with scores of 5% or above more rarely.
What it means for my dog
Your dog’s Wolfiness Score is not a measure of recent dog-wolf hybridization and does not necessarily indicate that your dog has some recent wolf ancestors. (If your dog has recent wolf ancestors, you will see that in the breed mix report.) Instead, the Wolfiness Score is based on the number of ancient genetic variants your dog has in our unique Wolfiness marker panel. Wolfiness scores up to 10% are almost always due to ancient wolf genes that survived many generations, rather than any recent wolf ancestors. These ancient genes may be a few thousand years old, or may even date back to the original domestication event 15,000 years ago. They are bits of a wild past that survive in your dog!
The science
Your dog’s Wolfiness Score is based on hundreds of markers across the genome where dogs (or almost all of them) are the same, but wolves tend to be different. These markers are thought to be related to "domestication gene sweeps" where early dogs were selected for some trait. Scientists have known about “domestication gene sweeps” for years, but do not yet know why each sweep occurred. By finding rare dogs carrying an ancient variant at a certain marker, we can make associations with behavior, size, metabolism, and development that likely caused these unique signatures of “doggyness” in the genome.
Predicted Adult Weight
How does weight matter?
For people with puppies, you probably want to know how big of a crate to buy or just how big to expect your dog to become. But genetic weight is also useful for people with fully grown dogs. Just like with people, overweight and obese dogs suffer reduced length and quality of life. They can develop chronic health conditions and suffer from limited mobility and other issues. While over half of American dogs are overweight or obese, fewer than 15% of their owners realize it. By comparing your dog’s weight to their genetic predicted weight you have one more piece of information about their ideal weight. With this and other pieces of information like weight history and body condition, you and your veterinarian may want to discuss your dog’s diet, exercise, and weight control plan to give your pup the longest, healthiest life possible.
How do we predict weight?
Our test is the only dog DNA test that provides true genetic size not based just on breed ancestry but based on over a dozen genes known to influence a dog’s weight. It uses the most advanced science to determine your dog’s expected weight based on their sex, the combination of these genes, and breed-specific modifiers.
How accurate is the predicted weight?
Unlike in people, healthy weight in dogs is controlled largely by only a few genes. Our algorithm explains over 85% of the variance in healthy adult weight. However, due to a few as-yet-undiscovered genes and genetic interactions that affect size, this algorithm sometimes misses. Occasionally it misses by a fairly large amount especially when a dog has a breed with an unknown size-influencing gene. If we have missed your dog’s weight, your dog may be a scientific discovery waiting to happen! Please be sure to go to the Research tab and complete the Getting to know your dog survey, where you can answer questions about your dog’s current weight and body shape. This information will inform our ongoing research into the genetics of size and weight in dogs.
Haplotypes
Revealing your dog’s ancient heritage
Haplotypes are particular DNA sequences that are inherited entirely from a dog’s mom (maternal) or dad (paternal).
Because they are inherited whole, your dog and his or her mom share the exact same maternal haplotype. If you have a male dog, your dog and his dad share the exact same paternal haplotype (female dogs don’t inherit paternal haplotypes).
Because most breeds were started with only a few individual dogs, many breeds are dominated by only one or a few haplotypes.
Haplogroups
Revealing your dog’s ancient heritage
Haplogroups are groups of similar DNA sequences (called haplotypes) that are inherited entirely from the mother (maternal) or father (paternal) and don’t get shuffled up like other parts of your dog’s genome.
These groups all originally descend from one male or female wolf, usually one that lived tens of thousands of years ago. Because they are inherited whole and not shuffled like other DNA, they can be used to trace the ancestral routes that dogs took around the globe en route to your home.
Only male dogs have paternal haplogroups because they are determined by the Y chromosome, which only male dogs have. Both males and females have maternal haplogroups, which come from a part of DNA called the mitochondrial DNA.
Breed analysis
Breed analysis is based on comparing your dog’s DNA with the DNA of dogs from over 350 breeds, types and varieties.How are Darwin's ancestors represented in his DNA?
All dogs are related and share some DNA. Siblings share lots of their DNA (half of it in fact), cousins share a bit less (an eighth), and so on. Because dog breeds are made up of a closed group of dogs, all dogs in that breed share a lot of their DNA, typically about as much as second cousins, though it varies by breed. Different breeds that are closely related share somewhat less DNA, and dogs from very different breeds share even less DNA (but still much more DNA than either dog shares with a cat).
DNA is inherited in pieces, called chromosomes, that are passed along from parent to offspring. Each generation, these chromosomes are broken up and shuffled a bit in a process known as recombination. So, the length of the segments your dog shares with his ancestors decreases with each generation above him: he shares longer segments with his mom than his grandma, longer segments with his grandma than his great-grandma, and so on.
How does Embark know which breeds are in Darwin?
We can use the length of segments Darwin shares with our reference dogs to see how many generations it has been since they last shared an ancestor. Long segments of DNA that are identical to known purebred dogs tell Embark's scientists that Darwin has, without a doubt, a relative from that breed. By testing thousands of genetic markers, we build up his genes one DNA segment at a time, to learn the ancestry with great certainty.
What does this mean for Darwin's looks and behavior?
Look closely and you'll probably find Darwin has some physical and/or behavioral resemblance with his ancestor's breeds. The exact similarity depends on which parts of DNA Darwin shares with each breed. Some traits associated with each breed are listed in the Breed & Ancestry section of our website. Embark will tell you even more about Darwin's traits soon!
P.S. In a small proportion of cases, we find dogs that don’t share segments with other dogs we have tested, indicating the presence of a rare breed that is not part of our reference panel or possibly a true "village dog" without any purebred relatives at all. In these rare cases we contact the owner to find out more and let them know about their unique dog before they get their results. With this in-depth detective work, we are pushing science forward by identifying genetically unique groups of dogs.
Still have questions?
Let us know with our contact form.
What are “Dogs Like Darwin?”
“Dogs Like Darwin” are based on the percentage of breeds the two dogs have in common. For example, two dogs that are both 27% Golden Retriever and 73% Poodle will have a score of 100%. Sometimes dogs with high scores look alike, and sometimes they don’t — either way the comparison is based on each dog’s unique DNA.
No bio has been provided yet
Instagram tag
@Darwinwonderdog
Place of Birth
Columbus, Indiana, USA
Current Location
Indianapolis, Indiana, USA
From
Columbus, Indiana, USA
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Genetic Breed Result
Embark Supermutt analysis
What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:
Shetland Sheepdog
Shetland Sheepdogs are a lively, smart and athletic herding dogs that also makes a great family pet.
Learn More
Poodle (Small)
A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.
Learn More
Lhasa Apso
An independent breed, the Lhasa's goal in life is not necessarily to please their master. The Lhasa Apso is a small, hardy breed with a beautiful cloak of hair that parts down the back from head to tail. Their temperament is unique: joyful and mischievous, dignified and aloof. Popular in the show ring, the breed also excels at activities that provide constant challenges, such as agility.
Learn More
Rat Terrier
The Rat Terrier is an American dog breed with a background as a farm dog and hunting companion.
Learn More
American Eskimo Dog
American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.
Learn More
Cocker Spaniel
Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.
Learn More
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Dogs Like Darwin
Discover dogs who share a similar breed mix to Darwin. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!
Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.
Building blocks of life
See which breed every part of Darwin’s DNA comes from!
Genes from your dog’s breeds serve as the building blocks to creating your unique pooch
Dogs have 39 pairs of chromosomes, almost double humans who have 23. 38 of those pairs are the same for all dogs while the 39th is the sex chromosomes - two X’s for females and one X and one Y for males. One copy of each chromosome came from your dog’s mother and one from your dog’s father. Each copy contains between 24 million and 123 million bases, or letters of DNA code, for 2.5 billion total letters inherited from each parent. This chromosome illustration shows a representation of each of your dog’s 38 pairs of chromosomes (excluding the X and Y sex chromosomes).
Because the members of a breed have similar stretches of DNA, we can use our panel of thousands of genetic markers to determine what part of each chromosome in your dog came from what breed. For each pair of chromosomes, your dog’s mom and dad each gave your dog one copy of that chromosome, for a grand total of 78 chromosomes. So if your dog’s mom was a poodle and dad was a schnauzer then the painting would show one complete poodle and one complete schnauzer chromosome for each pair. The more complex your dog’s ancestry, the more complex the painting, as in each generation recombination (the splitting apart and "shuffling around" of genes between paired chromosomes) mixes up bits of chromosome from grandparents, great-grandparents, and beyond.
Each trait your dog exhibits, such as fur shedding, is based on the letter at one or more locations in your dog’s genome. For example the location determining if your dog sheds their fur is located on chromosome 1. Some other traits, like size, are complexly inherited from many locations, including ones on chromosomes 1, 3, 4, 7, 10, 15, and more. Your dog looks the way it does not because of averaging or blending the breeds that form it, but because specific traits were inherited from specific breeds. That’s one reason your mix may look, act, and have certain health issues much more like one breed than another!
DNA Breed Origins
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Changes to this dog’s profile
- On 10/22/2020 changed handle from "darwin85" to "darwin0928"
Our policy is that each dog’s profile should accurately portray the dog to which the genetic reports belong.
To help ensure adherence to this policy, we show here any changes that have been made to the name or handle (web address) of this dog.
If you believe that this profile is in violation of this policy, you may contact us to report it.
Health Summary
Darwin is at increased risk for one genetic health condition.
And inherited one variant that you should learn more about.
Multiple Drug Sensitivity
How to interpret this result
Darwin has one copy of a variant at the ABCB1 gene and is at risk for displaying adverse drug reactions. While he may not be as severely affected as a dog with two copies of the ABCB1 drug sensitivity allele, normal dosages of drugs could still have potentially severe effects on Darwin. Please inform your veterinarian that Darwin carries this variant; it is essential that they know this information before prescribing drugs.
What is Multiple Drug Sensitivity?
Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with a mutation in the ABCB1 gene.
ALT Activity
Darwin inherited one copy of the variant we tested
Why is this important to your vet?
Darwin has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Darwin has this genotype, as ALT is often used as an indicator of liver health and Darwin is likely to have a lower than average resting ALT activity. As such, an increase in Darwin’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
Thrombopathia
Identified in American Eskimo Dogs
Variant not detected
Von Willebrand Disease Type III, Type III vWD
Identified in Shetland Sheepdogs
Variant not detected
Von Willebrand Disease Type I, Type I vWD
Identified in Small Poodles
Variant not detected
Congenital Hypothyroidism
Identified in Rat Terriers
Variant not detected
Progressive Retinal Atrophy, CNGA
Identified in Shetland Sheepdogs
Variant not detected
Progressive Retinal Atrophy, prcd
Identified in American Eskimo Dogs, Cocker Spaniels, and more
Variant not detected
Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1
Identified in Lhasa Apsos
Variant not detected
Collie Eye Anomaly
Identified in Shetland Sheepdogs
Variant not detected
Primary Lens Luxation
Identified in American Eskimo Dogs and Rat Terriers
Variant not detected
Familial Nephropathy
Identified in Cocker Spaniels
Variant not detected
Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency
Identified in Cocker Spaniels
Variant not detected
GM2 Gangliosidosis
Identified in Small Poodles
Variant not detected
Degenerative Myelopathy, DM
Identified in American Eskimo Dogs and Shetland Sheepdogs
Variant not detected
Neonatal Encephalopathy with Seizures, NEWS
Identified in Small Poodles
Variant not detected
Acral Mutilation Syndrome
Identified in Cocker Spaniels
Variant not detected
Exercise-Induced Collapse, EIC
Identified in Cocker Spaniels
Variant not detected
Oculocutaneous Albinism, OCA
Identified in Lhasa Apsos
Variant not detected
Osteochondrodysplasia
Identified in Small Poodles
Variant not detected
Intervertebral Disc Disease (Type I)
Identified in Cocker Spaniels and Small Poodles
Variant not detected
Additional Genetic Conditions
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What is a linkage test?
DNA sequences that are close together on a chromosome tend to be inherited together. Because of this, we can use genetic variation surrounding a specific variant (i.e. "linked" to it) to infer the presence or absence of a variant that is associated with a health condition or trait.
Linkage tests are not as predictive of your dog’s true genotype as direct assays, which we use on most other genetic conditions we test for.
Traits
Explore the genetics behind your dog’s appearance and size.
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Base Coat Color
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Coat Color Modifiers
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Coat Traits
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Other Body Features
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Body Size
No Result
For every test, we run multiple assays to ensure the accuracy of the results we deliver. For your dog, one or more of these produced inconclusive or low confident results. Therefore, we are not able to provide you with a result at this time.
Performance
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Through Darwin’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.
A1b
A411
A1b
This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!
A411
Part of the A1b haplogroup, this haplotype occurs most frequently in Border Collies, Australian Cattle Dogs, and Australian Shepherds.
A1b is the most common haplogroup found in German Shepherds.
Explore
Through Darwin’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.
A1b
Ha.7
A1b
For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.
Ha.7
Part of the A1b haplogroup, this haplotype is found in village dogs from Lebanon and Indonesia. Among breeds, it is also found in Miniature Schnauzer and Toy Poodle.
Great Danes and Pomeranians have this in common!