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Darla Ann (Darla)

Mixed Ancestry

“Darla Ann is 1 of 8 puppies rescued from Louisiana in 2020 at 8 weeks old.”

Place of Birth

Louisiana, USA

Current Location

Indian Head, Maryland, USA

From

Last Chance Animal Rescue, Bensville Road, Waldorf, MD, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Miniature Schnauzer

Miniature Schnauzers are an alert and spirited breed with guard dog tendencies.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Dogs Like Darla Ann (Darla)

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Discover dogs who share a similar breed mix to Darla Ann (Darla). A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
American Pit Bull Terrier
Siberian Husky
Cocker Spaniel
Miniature Schnauzer
Labrador Retriever
Supermutt

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Changes to this dog’s profile
  • On 7/1/2022 changed name from "Darla Ann" to "Darla Ann (Darla)"
Here’s what Darla Ann (Darla)’s family tree may have looked like.
Darla Ann (Darla)
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed American Pit Bull Terrier mix American Pit Bull Terrier / Miniature Schnauzer mix Cocker Spaniel / Labrador Retriever mix American Pit Bull Terrier Siberian Husky / American Pit Bull Terrier mix American Pit Bull Terrier Miniature Schnauzer mix Cocker Spaniel mix Labrador Retriever mix American Pit Bull Terrier American Pit Bull Terrier Siberian Husky American Pit Bull Terrier mix
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Darla Ann (Darla)’s breed mix.

Breed Reveal Video

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Health Summary

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Darla Ann (Darla) is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Darla Ann (Darla) inherited one copy of the variant we tested

How to interpret this result

Darla Ann (Darla) has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Urate Kidney & Bladder Stones

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Darla Ann (Darla) inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Darla Ann (Darla)’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Darla Ann (Darla) is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

Breed-Relevant Genetic Conditions

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Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd

Identified in Cocker Spaniels and Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

X-Linked Progressive Retinal Atrophy 1, XL-PRA1

Identified in Siberian Huskies

Day Blindness

Identified in Labrador Retrievers

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Familial Nephropathy

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

GM1 Gangliosidosis

Identified in Siberian Huskies

Persistent Mullerian Duct Syndrome, PMDS

Identified in Miniature Schnauzers

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in Labrador Retrievers and Siberian Huskies

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Narcolepsy

Identified in Labrador Retrievers

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Ullrich-like Congenital Muscular Dystrophy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels and Labrador Retrievers

Myotonia Congenita

Identified in Miniature Schnauzers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Demyelinating Polyneuropathy

Identified in Miniature Schnauzers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Darla Ann (Darla)’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A370

Map

A1b

Darla Ann (Darla)’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A370

Darla Ann (Darla)’s Haplotype

Part of the large A1b haplogroup, this haplotype occurs most commonly in Cocker Spaniels. It’s a rare find!

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Darla Ann (Darla) inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Darla Ann (Darla) is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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